Ca2+ signal through inositol trisphosphate receptors for cardiovascular development and pathophysiology of pulmonary arterial hypertension

Akimichi Shibata, Keiko Uchida, Katsuhiko Mikoshiba, Hiroyuki Yamagishi

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Inositol triphosphate receptor (IP3R) is an intracellular Ca2+ release channel located on the membrane of the sarco/endoplasmic reticulum (SR/ER), a major intracellular storage site for Ca2+. There are three subtypes of IP3R the pathophysiology of many organs [1].

Original languageEnglish
Title of host publicationMolecular Mechanism of Congenital Heart Disease and Pulmonary Hypertension
PublisherSpringer Singapore
Pages97-99
Number of pages3
ISBN (Electronic)9789811511851
ISBN (Print)9789811511844
DOIs
Publication statusPublished - 2020 Jan 1

Keywords

  • Calcium signaling
  • Cardiovascular system
  • Inositol trisphosphate receptor
  • Pulmonary arterial hypertension

ASJC Scopus subject areas

  • Medicine(all)

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