Calcium phosphate mineralization induced by synthetic peptides having different distributions in simulated body fluids

Mineo Hashizume; Noriaki Kamaya; Yuki Uchida; Teruhiko Matsubara; Toshinori Sato

doi:10.1246/cl.2012.588

Calcium phosphate mineralization induced by synthetic peptides having different distributions in simulated body fluids

Mineo Hashizume, Noriaki Kamaya, Yuki Uchida, Teruhiko Matsubara, Toshinori Sato

Department of Biosciences and Informatics

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

Synthetic peptides having hydroxyapatite binding ability can induce calcium phosphate (CaP) mineralization in simulated body fluids. The peptides freely dispersed in the solution induce formation of peptideCaP hybrids having sheet-like morphologies, whereas immobilized on solid substrates they induce hydroxyapatite deposition on the substrate surfaces. The results clearly show that distribution of the peptides affects their mineralization properties.

Original language	English
Pages (from-to)	588-590
Number of pages	3
Journal	Chemistry Letters
Volume	41
Issue number	6
DOIs	https://doi.org/10.1246/cl.2012.588
Publication status	Published - 2012 Jun 6

ASJC Scopus subject areas

Chemistry(all)

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10.1246/cl.2012.588

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abstract = "Synthetic peptides having hydroxyapatite binding ability can induce calcium phosphate (CaP) mineralization in simulated body fluids. The peptides freely dispersed in the solution induce formation of peptideCaP hybrids having sheet-like morphologies, whereas immobilized on solid substrates they induce hydroxyapatite deposition on the substrate surfaces. The results clearly show that distribution of the peptides affects their mineralization properties.",

author = "Mineo Hashizume and Noriaki Kamaya and Yuki Uchida and Teruhiko Matsubara and Toshinori Sato",

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AU - Hashizume, Mineo

AU - Kamaya, Noriaki

AU - Uchida, Yuki

AU - Matsubara, Teruhiko

AU - Sato, Toshinori

PY - 2012/6/6

Y1 - 2012/6/6

N2 - Synthetic peptides having hydroxyapatite binding ability can induce calcium phosphate (CaP) mineralization in simulated body fluids. The peptides freely dispersed in the solution induce formation of peptideCaP hybrids having sheet-like morphologies, whereas immobilized on solid substrates they induce hydroxyapatite deposition on the substrate surfaces. The results clearly show that distribution of the peptides affects their mineralization properties.

AB - Synthetic peptides having hydroxyapatite binding ability can induce calcium phosphate (CaP) mineralization in simulated body fluids. The peptides freely dispersed in the solution induce formation of peptideCaP hybrids having sheet-like morphologies, whereas immobilized on solid substrates they induce hydroxyapatite deposition on the substrate surfaces. The results clearly show that distribution of the peptides affects their mineralization properties.

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Calcium phosphate mineralization induced by synthetic peptides having different distributions in simulated body fluids

Abstract

ASJC Scopus subject areas

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