Camptocormia in Japanese patients with Parkinson's disease

A multicenter study

Morinobu Seki, Kazushi Takahashi, Atsuo Koto, Ban Mihara, Yoko Morita, Kazuo Isozumi, Kouichi Ohta, Kazuhiro Muramatsu, Jun Gotoh, Keiji Yamaguchi, Yutaka Tomita, Hideki Sato, Yoshihiro Nihei, Satoko Iwasawa, Norihiro Suzuki

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

Objective: The aim of this work was to investigate the prevalence of camptocormia and the clinical characteristics of patients with camptocormia in a large population of PD patients. Background: Although camptocormia has been recognized as a prominent phenomenon in PD, the previous epidemiological reports were limited, especially in terms of sample size. Methods:: We evaluated 531 PD patients (disease duration: 7.0 ± 5.5 years, mean ± standard deviation). We examined their clinical features and the prevalence of camptocormia. Results: Camptocormia was detected in 22 patients (4.1%) and found in patients who were older and had more severe motor symptoms and a higher levodopa (L-dopa) dose (P < 0.05), compared to the patients without camptocormia. Patients with camptocormia showed significantly higher frequencies of autonomic symptoms, such as constipation and urinary incontinence (P < 0.05). Conclusions: Camptocormia is uncommon in PD and is associated with disease severity, higher L-dopa dose and higher frequencies of autonomic symptoms.

Original languageEnglish
Pages (from-to)2567-2571
Number of pages5
JournalMovement Disorders
Volume26
Issue number14
DOIs
Publication statusPublished - 2011 Dec

Fingerprint

Multicenter Studies
Parkinson Disease
Levodopa
Camptocormia
Urinary Incontinence
Constipation
Sample Size
Population

Keywords

  • Bent spine
  • Camptocormia
  • Japanese patients
  • Nonmotor symptom
  • Parkinson's disease

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

Cite this

Seki, M., Takahashi, K., Koto, A., Mihara, B., Morita, Y., Isozumi, K., ... Suzuki, N. (2011). Camptocormia in Japanese patients with Parkinson's disease: A multicenter study. Movement Disorders, 26(14), 2567-2571. https://doi.org/10.1002/mds.23955

Camptocormia in Japanese patients with Parkinson's disease : A multicenter study. / Seki, Morinobu; Takahashi, Kazushi; Koto, Atsuo; Mihara, Ban; Morita, Yoko; Isozumi, Kazuo; Ohta, Kouichi; Muramatsu, Kazuhiro; Gotoh, Jun; Yamaguchi, Keiji; Tomita, Yutaka; Sato, Hideki; Nihei, Yoshihiro; Iwasawa, Satoko; Suzuki, Norihiro.

In: Movement Disorders, Vol. 26, No. 14, 12.2011, p. 2567-2571.

Research output: Contribution to journalArticle

Seki, M, Takahashi, K, Koto, A, Mihara, B, Morita, Y, Isozumi, K, Ohta, K, Muramatsu, K, Gotoh, J, Yamaguchi, K, Tomita, Y, Sato, H, Nihei, Y, Iwasawa, S & Suzuki, N 2011, 'Camptocormia in Japanese patients with Parkinson's disease: A multicenter study', Movement Disorders, vol. 26, no. 14, pp. 2567-2571. https://doi.org/10.1002/mds.23955
Seki M, Takahashi K, Koto A, Mihara B, Morita Y, Isozumi K et al. Camptocormia in Japanese patients with Parkinson's disease: A multicenter study. Movement Disorders. 2011 Dec;26(14):2567-2571. https://doi.org/10.1002/mds.23955
Seki, Morinobu ; Takahashi, Kazushi ; Koto, Atsuo ; Mihara, Ban ; Morita, Yoko ; Isozumi, Kazuo ; Ohta, Kouichi ; Muramatsu, Kazuhiro ; Gotoh, Jun ; Yamaguchi, Keiji ; Tomita, Yutaka ; Sato, Hideki ; Nihei, Yoshihiro ; Iwasawa, Satoko ; Suzuki, Norihiro. / Camptocormia in Japanese patients with Parkinson's disease : A multicenter study. In: Movement Disorders. 2011 ; Vol. 26, No. 14. pp. 2567-2571.
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abstract = "Objective: The aim of this work was to investigate the prevalence of camptocormia and the clinical characteristics of patients with camptocormia in a large population of PD patients. Background: Although camptocormia has been recognized as a prominent phenomenon in PD, the previous epidemiological reports were limited, especially in terms of sample size. Methods:: We evaluated 531 PD patients (disease duration: 7.0 ± 5.5 years, mean ± standard deviation). We examined their clinical features and the prevalence of camptocormia. Results: Camptocormia was detected in 22 patients (4.1{\%}) and found in patients who were older and had more severe motor symptoms and a higher levodopa (L-dopa) dose (P < 0.05), compared to the patients without camptocormia. Patients with camptocormia showed significantly higher frequencies of autonomic symptoms, such as constipation and urinary incontinence (P < 0.05). Conclusions: Camptocormia is uncommon in PD and is associated with disease severity, higher L-dopa dose and higher frequencies of autonomic symptoms.",
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