Cancer survivors exhibit a different relationship between muscle strength and health-related quality of life/fatigue compared to healthy subjects

S. Morishita, A. Tsubaki, J. B. Fu, Y. Mitobe, H. Onishi, Tetsuya Tsuji

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

We investigated the difference in relationship between muscle strength and quality of life (QOL)/fatigue in long-term cancer survivors and healthy subjects. Thirty-six cancer survivors and 29 healthy subjects were assessed for body composition and bone status at the calcaneus using the Osteo Sono Assessment Index. Muscle strength was evaluated via handgrip and knee extensor strength. Health-related QOL was assessed using the Medical Outcome Study 36-item Short-Form Health Survey. Fatigue was measured using the brief fatigue inventory. Cancer survivors exhibited lower QOL scores in the physical functioning, physical role function, bodily pain and general health domains (p <.05). Grip and knee extension muscle strength in cancer survivors was positively correlated with the physical function and bodily pain of QOL (p <.05). The usual fatigue subscale score was only significantly higher in cancer survivors than in healthy subjects (p <.05). However, there were no correlations between muscle strength and fatigue in cancer survivors. Our results showed that muscle strength was an important factor for improving QOL in cancer survivors. We believe that the findings of this study will be relevant in the context of planning rehabilitation for cancer survivors.

Original languageEnglish
Article numbere12856
JournalEuropean Journal of Cancer Care
Volume27
Issue number4
DOIs
Publication statusPublished - 2018 Jul 1

Fingerprint

Muscle Strength
Fatigue
Survivors
Healthy Volunteers
Quality of Life
Neoplasms
Knee
Pain
Calcaneus
Muscle Fatigue
Hand Strength
Body Composition
Health Surveys
Rehabilitation
Outcome Assessment (Health Care)
Bone and Bones
Equipment and Supplies
Health

Keywords

  • cancer
  • exercise
  • quality of life

ASJC Scopus subject areas

  • Oncology

Cite this

Cancer survivors exhibit a different relationship between muscle strength and health-related quality of life/fatigue compared to healthy subjects. / Morishita, S.; Tsubaki, A.; Fu, J. B.; Mitobe, Y.; Onishi, H.; Tsuji, Tetsuya.

In: European Journal of Cancer Care, Vol. 27, No. 4, e12856, 01.07.2018.

Research output: Contribution to journalArticle

@article{598195de6ca14a1ea34b753a55471f56,
title = "Cancer survivors exhibit a different relationship between muscle strength and health-related quality of life/fatigue compared to healthy subjects",
abstract = "We investigated the difference in relationship between muscle strength and quality of life (QOL)/fatigue in long-term cancer survivors and healthy subjects. Thirty-six cancer survivors and 29 healthy subjects were assessed for body composition and bone status at the calcaneus using the Osteo Sono Assessment Index. Muscle strength was evaluated via handgrip and knee extensor strength. Health-related QOL was assessed using the Medical Outcome Study 36-item Short-Form Health Survey. Fatigue was measured using the brief fatigue inventory. Cancer survivors exhibited lower QOL scores in the physical functioning, physical role function, bodily pain and general health domains (p <.05). Grip and knee extension muscle strength in cancer survivors was positively correlated with the physical function and bodily pain of QOL (p <.05). The usual fatigue subscale score was only significantly higher in cancer survivors than in healthy subjects (p <.05). However, there were no correlations between muscle strength and fatigue in cancer survivors. Our results showed that muscle strength was an important factor for improving QOL in cancer survivors. We believe that the findings of this study will be relevant in the context of planning rehabilitation for cancer survivors.",
keywords = "cancer, exercise, quality of life",
author = "S. Morishita and A. Tsubaki and Fu, {J. B.} and Y. Mitobe and H. Onishi and Tetsuya Tsuji",
year = "2018",
month = "7",
day = "1",
doi = "10.1111/ecc.12856",
language = "English",
volume = "27",
journal = "European Journal of Cancer Care",
issn = "0961-5423",
publisher = "Wiley-Blackwell",
number = "4",

}

TY - JOUR

T1 - Cancer survivors exhibit a different relationship between muscle strength and health-related quality of life/fatigue compared to healthy subjects

AU - Morishita, S.

AU - Tsubaki, A.

AU - Fu, J. B.

AU - Mitobe, Y.

AU - Onishi, H.

AU - Tsuji, Tetsuya

PY - 2018/7/1

Y1 - 2018/7/1

N2 - We investigated the difference in relationship between muscle strength and quality of life (QOL)/fatigue in long-term cancer survivors and healthy subjects. Thirty-six cancer survivors and 29 healthy subjects were assessed for body composition and bone status at the calcaneus using the Osteo Sono Assessment Index. Muscle strength was evaluated via handgrip and knee extensor strength. Health-related QOL was assessed using the Medical Outcome Study 36-item Short-Form Health Survey. Fatigue was measured using the brief fatigue inventory. Cancer survivors exhibited lower QOL scores in the physical functioning, physical role function, bodily pain and general health domains (p <.05). Grip and knee extension muscle strength in cancer survivors was positively correlated with the physical function and bodily pain of QOL (p <.05). The usual fatigue subscale score was only significantly higher in cancer survivors than in healthy subjects (p <.05). However, there were no correlations between muscle strength and fatigue in cancer survivors. Our results showed that muscle strength was an important factor for improving QOL in cancer survivors. We believe that the findings of this study will be relevant in the context of planning rehabilitation for cancer survivors.

AB - We investigated the difference in relationship between muscle strength and quality of life (QOL)/fatigue in long-term cancer survivors and healthy subjects. Thirty-six cancer survivors and 29 healthy subjects were assessed for body composition and bone status at the calcaneus using the Osteo Sono Assessment Index. Muscle strength was evaluated via handgrip and knee extensor strength. Health-related QOL was assessed using the Medical Outcome Study 36-item Short-Form Health Survey. Fatigue was measured using the brief fatigue inventory. Cancer survivors exhibited lower QOL scores in the physical functioning, physical role function, bodily pain and general health domains (p <.05). Grip and knee extension muscle strength in cancer survivors was positively correlated with the physical function and bodily pain of QOL (p <.05). The usual fatigue subscale score was only significantly higher in cancer survivors than in healthy subjects (p <.05). However, there were no correlations between muscle strength and fatigue in cancer survivors. Our results showed that muscle strength was an important factor for improving QOL in cancer survivors. We believe that the findings of this study will be relevant in the context of planning rehabilitation for cancer survivors.

KW - cancer

KW - exercise

KW - quality of life

UR - http://www.scopus.com/inward/record.url?scp=85050475896&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85050475896&partnerID=8YFLogxK

U2 - 10.1111/ecc.12856

DO - 10.1111/ecc.12856

M3 - Article

C2 - 29767832

AN - SCOPUS:85050475896

VL - 27

JO - European Journal of Cancer Care

JF - European Journal of Cancer Care

SN - 0961-5423

IS - 4

M1 - e12856

ER -