TY - JOUR
T1 - Capsular type and antibiotic resistance in Streptococcus agalactiae isolates from patients, ranging from newborns to the elderly, with invasive infections
AU - Murayama, Somay Yamagata
AU - Seki, Chizuko
AU - Sakata, Hiroshi
AU - Sunaoshi, Katsuhiko
AU - Nakayama, Eiichi
AU - Iwata, Satoshi
AU - Sunakawa, Keisuke
AU - Ubukata, Kimiko
PY - 2009/6
Y1 - 2009/6
N2 - Streptococcus agalactiae isolates (n = 189) from patients with invasive infections were analyzed for capsular type by PCR, for antimicrobial susceptibility, and for the presence of resistance genes. In contrast to the predominance of capsular type III in children, types Ib and V were most common among adults. All 45 levofloxacin-resistant strains had two amino acid substitutions, Ser81Leu in the gyrA gene and Ser79Phe in the parC gene, and showed similar pulsed-field gel electrophoresis patterns.
AB - Streptococcus agalactiae isolates (n = 189) from patients with invasive infections were analyzed for capsular type by PCR, for antimicrobial susceptibility, and for the presence of resistance genes. In contrast to the predominance of capsular type III in children, types Ib and V were most common among adults. All 45 levofloxacin-resistant strains had two amino acid substitutions, Ser81Leu in the gyrA gene and Ser79Phe in the parC gene, and showed similar pulsed-field gel electrophoresis patterns.
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U2 - 10.1128/AAC.01716-08
DO - 10.1128/AAC.01716-08
M3 - Article
C2 - 19332682
AN - SCOPUS:67049134632
VL - 53
SP - 2650
EP - 2653
JO - Antimicrobial Agents and Chemotherapy
JF - Antimicrobial Agents and Chemotherapy
SN - 0066-4804
IS - 6
ER -
