Capsular type and antibiotic resistance in Streptococcus agalactiae isolates from patients, ranging from newborns to the elderly, with invasive infections

Somay Yamagata Murayama; Chizuko Seki; Hiroshi Sakata; Katsuhiko Sunaoshi; Eiichi Nakayama; Satoshi Iwata; Keisuke Sunakawa; Kimiko Ubukata

doi:10.1128/AAC.01716-08

Capsular type and antibiotic resistance in Streptococcus agalactiae isolates from patients, ranging from newborns to the elderly, with invasive infections

Somay Yamagata Murayama, Chizuko Seki, Hiroshi Sakata, Katsuhiko Sunaoshi, Eiichi Nakayama, Satoshi Iwata, Keisuke Sunakawa, Kimiko Ubukata

Department of Infectious Diseases

Research output: Contribution to journal › Article › peer-review

62 Citations (Scopus)

Abstract

Streptococcus agalactiae isolates (n = 189) from patients with invasive infections were analyzed for capsular type by PCR, for antimicrobial susceptibility, and for the presence of resistance genes. In contrast to the predominance of capsular type III in children, types Ib and V were most common among adults. All 45 levofloxacin-resistant strains had two amino acid substitutions, Ser₈₁Leu in the gyrA gene and Ser₇₉Phe in the parC gene, and showed similar pulsed-field gel electrophoresis patterns.

Original language	English
Pages (from-to)	2650-2653
Number of pages	4
Journal	Antimicrobial Agents and Chemotherapy
Volume	53
Issue number	6
DOIs	https://doi.org/10.1128/AAC.01716-08
Publication status	Published - 2009 Jun

ASJC Scopus subject areas

Pharmacology
Pharmacology (medical)
Infectious Diseases

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Capsular type and antibiotic resistance in Streptococcus agalactiae isolates from patients, ranging from newborns to the elderly, with invasive infections. / Murayama, Somay Yamagata; Seki, Chizuko; Sakata, Hiroshi; Sunaoshi, Katsuhiko; Nakayama, Eiichi; Iwata, Satoshi; Sunakawa, Keisuke; Ubukata, Kimiko.

In: Antimicrobial Agents and Chemotherapy, Vol. 53, No. 6, 06.2009, p. 2650-2653.

Research output: Contribution to journal › Article › peer-review

Murayama, Somay Yamagata ; Seki, Chizuko ; Sakata, Hiroshi ; Sunaoshi, Katsuhiko ; Nakayama, Eiichi ; Iwata, Satoshi ; Sunakawa, Keisuke ; Ubukata, Kimiko. / Capsular type and antibiotic resistance in Streptococcus agalactiae isolates from patients, ranging from newborns to the elderly, with invasive infections. In: Antimicrobial Agents and Chemotherapy. 2009 ; Vol. 53, No. 6. pp. 2650-2653.

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