Capsular type and antibiotic resistance in Streptococcus agalactiae isolates from patients, ranging from newborns to the elderly, with invasive infections

Somay Yamagata Murayama, Chizuko Seki, Hiroshi Sakata, Katsuhiko Sunaoshi, Eiichi Nakayama, Satoshi Iwata, Keisuke Sunakawa, Kimiko Ubukata

Research output: Contribution to journalArticle

60 Citations (Scopus)

Abstract

Streptococcus agalactiae isolates (n = 189) from patients with invasive infections were analyzed for capsular type by PCR, for antimicrobial susceptibility, and for the presence of resistance genes. In contrast to the predominance of capsular type III in children, types Ib and V were most common among adults. All 45 levofloxacin-resistant strains had two amino acid substitutions, Ser81Leu in the gyrA gene and Ser79Phe in the parC gene, and showed similar pulsed-field gel electrophoresis patterns.

Original languageEnglish
Pages (from-to)2650-2653
Number of pages4
JournalAntimicrobial Agents and Chemotherapy
Volume53
Issue number6
DOIs
Publication statusPublished - 2009 Jun 1

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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