TY - JOUR
T1 - Carbohydrate-modulated DNA photocleavage
T2 - Design, synthesis, and evaluation of novel glycosyl anthraquinones
AU - Toshima, Kazunobu
AU - Maeda, Yutaka
AU - Ouchi, Hiromi
AU - Asai, Akira
AU - Matsumura, Shuichi
N1 - Funding Information:
This research was partially supported by a Grant-in-Aid for Encouragement of Young Scientists from the Ministry of Education, Science, Sports and Culture, Japan, and a research grant of Keio University Special Grant-in-Aid for Innovative Collaborative Research Projects.
PY - 2000/10/2
Y1 - 2000/10/2
N2 - Novel and artificial anthraquinone-carbohydrate hybrids were designed and synthesized, and found to effectively cleave DNA under irradiation with a long wavelength UV light and also exhibit cytotoxicity against HeLa S3 cells. (C) 2000 Elsevier Science Ltd.
AB - Novel and artificial anthraquinone-carbohydrate hybrids were designed and synthesized, and found to effectively cleave DNA under irradiation with a long wavelength UV light and also exhibit cytotoxicity against HeLa S3 cells. (C) 2000 Elsevier Science Ltd.
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U2 - 10.1016/S0960-894X(00)00410-8
DO - 10.1016/S0960-894X(00)00410-8
M3 - Article
C2 - 11012020
AN - SCOPUS:0034597026
SN - 0960-894X
VL - 10
SP - 2163
EP - 2165
JO - Bioorganic and Medicinal Chemistry Letters
JF - Bioorganic and Medicinal Chemistry Letters
IS - 19
ER -