Cardiovascular health and cognitive functioning among centenarians: A comparison between the Tokyo and Georgia centenarian studies

Peter Martin, Yasuyuki Gondo, Yasumichi Arai, Yoshiko Ishioka, Mary Ann Johnson, L. Stephen Miller, John L. Woodard, Leonard W. Poon, Nobuyoshi Hirose

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Objectives:Centenarians have survived into very late life, but whether they reach very old age in good health remains unclear. The purpose of this study was to compare the cardiovascular health status and cognitive functioning of centenarians in the United States with centenarians in Japan.Design, Setting, and Participants:This cross-national design compared centenarians from the United States and Japan. The sample of U.S. centenarians was recruited from the Georgia Centenarian Study and included 287 centenarians. The sample of Japanese centenarians was recruited from the Tokyo Centenarian Study and included 304 centenarians.Measurements:Cognitive functioning was assessed with a mental status questionnaire, and cardiovascular disease by a health history assessment, blood pressure, and selected blood parameters.Results:The results suggest that Tokyo centenarians had lower disease experiences and BMI values, when compared to Georgia centenarians, but blood pressure was higher among Japanese centenarians. Lower levels of hemoglobin in Japanese centenarians and higher levels of C-reactive protein in Georgia were also found. The positive association of hypertension and albumin levels with cognitive functioning and the negative association of stroke occurrence with cognitive functioning were replicated in both countries. Differential effects were obtained for heart problems, BMI, and C-reactive protein (with positive effects for Tokyo centenarians, except for C-reactive protein).Conclusion:For extremely old individuals, some markers of cardiovascular disease are replicable across countries, whereas differential effects for cardiovascular health also need to be considered in cardiovascular health.

Original languageEnglish
JournalInternational Psychogeriatrics
DOIs
Publication statusPublished - 2019 Jan 1

Fingerprint

Tokyo
Health
C-Reactive Protein
Japan
Cardiovascular Diseases
Hypertension
Health Status

Keywords

  • cardiovascular health
  • centenarians
  • cognitive functioning

ASJC Scopus subject areas

  • Clinical Psychology
  • Gerontology
  • Geriatrics and Gerontology
  • Psychiatry and Mental health

Cite this

Cardiovascular health and cognitive functioning among centenarians : A comparison between the Tokyo and Georgia centenarian studies. / Martin, Peter; Gondo, Yasuyuki; Arai, Yasumichi; Ishioka, Yoshiko; Johnson, Mary Ann; Miller, L. Stephen; Woodard, John L.; Poon, Leonard W.; Hirose, Nobuyoshi.

In: International Psychogeriatrics, 01.01.2019.

Research output: Contribution to journalArticle

Martin, Peter ; Gondo, Yasuyuki ; Arai, Yasumichi ; Ishioka, Yoshiko ; Johnson, Mary Ann ; Miller, L. Stephen ; Woodard, John L. ; Poon, Leonard W. ; Hirose, Nobuyoshi. / Cardiovascular health and cognitive functioning among centenarians : A comparison between the Tokyo and Georgia centenarian studies. In: International Psychogeriatrics. 2019.
@article{577fa4c7655641d290e1bc73b6a21bf2,
title = "Cardiovascular health and cognitive functioning among centenarians: A comparison between the Tokyo and Georgia centenarian studies",
abstract = "Objectives:Centenarians have survived into very late life, but whether they reach very old age in good health remains unclear. The purpose of this study was to compare the cardiovascular health status and cognitive functioning of centenarians in the United States with centenarians in Japan.Design, Setting, and Participants:This cross-national design compared centenarians from the United States and Japan. The sample of U.S. centenarians was recruited from the Georgia Centenarian Study and included 287 centenarians. The sample of Japanese centenarians was recruited from the Tokyo Centenarian Study and included 304 centenarians.Measurements:Cognitive functioning was assessed with a mental status questionnaire, and cardiovascular disease by a health history assessment, blood pressure, and selected blood parameters.Results:The results suggest that Tokyo centenarians had lower disease experiences and BMI values, when compared to Georgia centenarians, but blood pressure was higher among Japanese centenarians. Lower levels of hemoglobin in Japanese centenarians and higher levels of C-reactive protein in Georgia were also found. The positive association of hypertension and albumin levels with cognitive functioning and the negative association of stroke occurrence with cognitive functioning were replicated in both countries. Differential effects were obtained for heart problems, BMI, and C-reactive protein (with positive effects for Tokyo centenarians, except for C-reactive protein).Conclusion:For extremely old individuals, some markers of cardiovascular disease are replicable across countries, whereas differential effects for cardiovascular health also need to be considered in cardiovascular health.",
keywords = "cardiovascular health, centenarians, cognitive functioning",
author = "Peter Martin and Yasuyuki Gondo and Yasumichi Arai and Yoshiko Ishioka and Johnson, {Mary Ann} and Miller, {L. Stephen} and Woodard, {John L.} and Poon, {Leonard W.} and Nobuyoshi Hirose",
year = "2019",
month = "1",
day = "1",
doi = "10.1017/S1041610218001813",
language = "English",
journal = "International Psychogeriatrics",
issn = "1041-6102",
publisher = "Cambridge University Press",

}

TY - JOUR

T1 - Cardiovascular health and cognitive functioning among centenarians

T2 - A comparison between the Tokyo and Georgia centenarian studies

AU - Martin, Peter

AU - Gondo, Yasuyuki

AU - Arai, Yasumichi

AU - Ishioka, Yoshiko

AU - Johnson, Mary Ann

AU - Miller, L. Stephen

AU - Woodard, John L.

AU - Poon, Leonard W.

AU - Hirose, Nobuyoshi

PY - 2019/1/1

Y1 - 2019/1/1

N2 - Objectives:Centenarians have survived into very late life, but whether they reach very old age in good health remains unclear. The purpose of this study was to compare the cardiovascular health status and cognitive functioning of centenarians in the United States with centenarians in Japan.Design, Setting, and Participants:This cross-national design compared centenarians from the United States and Japan. The sample of U.S. centenarians was recruited from the Georgia Centenarian Study and included 287 centenarians. The sample of Japanese centenarians was recruited from the Tokyo Centenarian Study and included 304 centenarians.Measurements:Cognitive functioning was assessed with a mental status questionnaire, and cardiovascular disease by a health history assessment, blood pressure, and selected blood parameters.Results:The results suggest that Tokyo centenarians had lower disease experiences and BMI values, when compared to Georgia centenarians, but blood pressure was higher among Japanese centenarians. Lower levels of hemoglobin in Japanese centenarians and higher levels of C-reactive protein in Georgia were also found. The positive association of hypertension and albumin levels with cognitive functioning and the negative association of stroke occurrence with cognitive functioning were replicated in both countries. Differential effects were obtained for heart problems, BMI, and C-reactive protein (with positive effects for Tokyo centenarians, except for C-reactive protein).Conclusion:For extremely old individuals, some markers of cardiovascular disease are replicable across countries, whereas differential effects for cardiovascular health also need to be considered in cardiovascular health.

AB - Objectives:Centenarians have survived into very late life, but whether they reach very old age in good health remains unclear. The purpose of this study was to compare the cardiovascular health status and cognitive functioning of centenarians in the United States with centenarians in Japan.Design, Setting, and Participants:This cross-national design compared centenarians from the United States and Japan. The sample of U.S. centenarians was recruited from the Georgia Centenarian Study and included 287 centenarians. The sample of Japanese centenarians was recruited from the Tokyo Centenarian Study and included 304 centenarians.Measurements:Cognitive functioning was assessed with a mental status questionnaire, and cardiovascular disease by a health history assessment, blood pressure, and selected blood parameters.Results:The results suggest that Tokyo centenarians had lower disease experiences and BMI values, when compared to Georgia centenarians, but blood pressure was higher among Japanese centenarians. Lower levels of hemoglobin in Japanese centenarians and higher levels of C-reactive protein in Georgia were also found. The positive association of hypertension and albumin levels with cognitive functioning and the negative association of stroke occurrence with cognitive functioning were replicated in both countries. Differential effects were obtained for heart problems, BMI, and C-reactive protein (with positive effects for Tokyo centenarians, except for C-reactive protein).Conclusion:For extremely old individuals, some markers of cardiovascular disease are replicable across countries, whereas differential effects for cardiovascular health also need to be considered in cardiovascular health.

KW - cardiovascular health

KW - centenarians

KW - cognitive functioning

UR - http://www.scopus.com/inward/record.url?scp=85061983532&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85061983532&partnerID=8YFLogxK

U2 - 10.1017/S1041610218001813

DO - 10.1017/S1041610218001813

M3 - Article

C2 - 30786950

AN - SCOPUS:85061983532

JO - International Psychogeriatrics

JF - International Psychogeriatrics

SN - 1041-6102

ER -