Carotid intima-media thickness and plaque in apparently healthy Japanese individuals with an estimated 10-year absolute risk of CAD death according to the Japan atherosclerosis society (JAS) guidelines 2012

The shiga epidemiological study of subclinical atherosclerosis (SESSA)

Aya Kadota, Katsuyuki Miura, Tomonori Okamura, Akira Fujiyoshi, Takayoshi Ohkubo, Takashi Kadowaki, Naoyuki Takashima, Takashi Hisamatsu, Yasuyuki Nakamura, Fumiyoshi Kasagi, Hiroshi Maegawa, Atsunori Kashiwagi, Hirotsugu Ueshima

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Aim: To examine whether subclinical atherosclerosis of the carotid arteries is concordant with the categories in the 2012 atherosclerosis prevention guidelines proposed by the Japan Atherosclerosis Society (JAS guidelines 2012), which adopted the estimated 10-year absolute risk of coronary artery disease (CAD) death in the NIPPON DATA80 Risk Assessment Chart. Methods: Between 2006 and 2008, 868 Japanese men 40 to 74 years of age without a history of cardiovascular disease were randomly selected from Kusatsu City, Japan. The intima media thickness (IMT) and plaque number from the common to internal carotid arteries were investigated using ultrasonography. The absolute risk of CAD death was estimated based on the individual risk factor data, and the mean IMT and plaque number in Categories I, II and III of the guidelines were examined. Results: The estimated 10-year absolute risk of CAD was directly related to the IMT (mean IMT (mean±SD) (mm) for a 10-year absolute risk of ≥2.0% and ≥5.0%: 0.88±0.18 and 0.95±0.19, respectively) and the plaque number. These results are compatible with the categories described by the guidelines (mean IMT (mean±SD) (mm) for Categories I, II, and III: 0.70±0.11, 0.81±0.16 and 0.88±0.18, respectively; mean plaque number: 0.9, 2.1 and 3, respectively). These findings were similar for Category III participants with or without DM and CKD. Conclusions: Subclinical atherosclerosis of the carotid arteries is concordant with the 10-year absolute risk of CAD and the categories in the JAS guidelines 2012.

Original languageEnglish
Pages (from-to)755-766
Number of pages12
JournalJournal of Atherosclerosis and Thrombosis
Volume20
Issue number10
DOIs
Publication statusPublished - 2013

Fingerprint

Carotid Intima-Media Thickness
Epidemiologic Studies
Coronary Artery Disease
Atherosclerosis
Japan
Guidelines
Carotid Arteries
Ultrasonography
Internal Carotid Artery
Risk assessment
Cardiovascular Diseases

Keywords

  • Absolute risk
  • Carotid atherosclerosis
  • Coronary artery disease (CAD)
  • Coronary heart disease (CHD)
  • Intima-media thickness
  • JAS guidelines

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Internal Medicine
  • Biochemistry, medical

Cite this

Carotid intima-media thickness and plaque in apparently healthy Japanese individuals with an estimated 10-year absolute risk of CAD death according to the Japan atherosclerosis society (JAS) guidelines 2012 : The shiga epidemiological study of subclinical atherosclerosis (SESSA). / Kadota, Aya; Miura, Katsuyuki; Okamura, Tomonori; Fujiyoshi, Akira; Ohkubo, Takayoshi; Kadowaki, Takashi; Takashima, Naoyuki; Hisamatsu, Takashi; Nakamura, Yasuyuki; Kasagi, Fumiyoshi; Maegawa, Hiroshi; Kashiwagi, Atsunori; Ueshima, Hirotsugu.

In: Journal of Atherosclerosis and Thrombosis, Vol. 20, No. 10, 2013, p. 755-766.

Research output: Contribution to journalArticle

Kadota, Aya ; Miura, Katsuyuki ; Okamura, Tomonori ; Fujiyoshi, Akira ; Ohkubo, Takayoshi ; Kadowaki, Takashi ; Takashima, Naoyuki ; Hisamatsu, Takashi ; Nakamura, Yasuyuki ; Kasagi, Fumiyoshi ; Maegawa, Hiroshi ; Kashiwagi, Atsunori ; Ueshima, Hirotsugu. / Carotid intima-media thickness and plaque in apparently healthy Japanese individuals with an estimated 10-year absolute risk of CAD death according to the Japan atherosclerosis society (JAS) guidelines 2012 : The shiga epidemiological study of subclinical atherosclerosis (SESSA). In: Journal of Atherosclerosis and Thrombosis. 2013 ; Vol. 20, No. 10. pp. 755-766.
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abstract = "Aim: To examine whether subclinical atherosclerosis of the carotid arteries is concordant with the categories in the 2012 atherosclerosis prevention guidelines proposed by the Japan Atherosclerosis Society (JAS guidelines 2012), which adopted the estimated 10-year absolute risk of coronary artery disease (CAD) death in the NIPPON DATA80 Risk Assessment Chart. Methods: Between 2006 and 2008, 868 Japanese men 40 to 74 years of age without a history of cardiovascular disease were randomly selected from Kusatsu City, Japan. The intima media thickness (IMT) and plaque number from the common to internal carotid arteries were investigated using ultrasonography. The absolute risk of CAD death was estimated based on the individual risk factor data, and the mean IMT and plaque number in Categories I, II and III of the guidelines were examined. Results: The estimated 10-year absolute risk of CAD was directly related to the IMT (mean IMT (mean±SD) (mm) for a 10-year absolute risk of ≥2.0{\%} and ≥5.0{\%}: 0.88±0.18 and 0.95±0.19, respectively) and the plaque number. These results are compatible with the categories described by the guidelines (mean IMT (mean±SD) (mm) for Categories I, II, and III: 0.70±0.11, 0.81±0.16 and 0.88±0.18, respectively; mean plaque number: 0.9, 2.1 and 3, respectively). These findings were similar for Category III participants with or without DM and CKD. Conclusions: Subclinical atherosclerosis of the carotid arteries is concordant with the 10-year absolute risk of CAD and the categories in the JAS guidelines 2012.",
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T1 - Carotid intima-media thickness and plaque in apparently healthy Japanese individuals with an estimated 10-year absolute risk of CAD death according to the Japan atherosclerosis society (JAS) guidelines 2012

T2 - The shiga epidemiological study of subclinical atherosclerosis (SESSA)

AU - Kadota, Aya

AU - Miura, Katsuyuki

AU - Okamura, Tomonori

AU - Fujiyoshi, Akira

AU - Ohkubo, Takayoshi

AU - Kadowaki, Takashi

AU - Takashima, Naoyuki

AU - Hisamatsu, Takashi

AU - Nakamura, Yasuyuki

AU - Kasagi, Fumiyoshi

AU - Maegawa, Hiroshi

AU - Kashiwagi, Atsunori

AU - Ueshima, Hirotsugu

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N2 - Aim: To examine whether subclinical atherosclerosis of the carotid arteries is concordant with the categories in the 2012 atherosclerosis prevention guidelines proposed by the Japan Atherosclerosis Society (JAS guidelines 2012), which adopted the estimated 10-year absolute risk of coronary artery disease (CAD) death in the NIPPON DATA80 Risk Assessment Chart. Methods: Between 2006 and 2008, 868 Japanese men 40 to 74 years of age without a history of cardiovascular disease were randomly selected from Kusatsu City, Japan. The intima media thickness (IMT) and plaque number from the common to internal carotid arteries were investigated using ultrasonography. The absolute risk of CAD death was estimated based on the individual risk factor data, and the mean IMT and plaque number in Categories I, II and III of the guidelines were examined. Results: The estimated 10-year absolute risk of CAD was directly related to the IMT (mean IMT (mean±SD) (mm) for a 10-year absolute risk of ≥2.0% and ≥5.0%: 0.88±0.18 and 0.95±0.19, respectively) and the plaque number. These results are compatible with the categories described by the guidelines (mean IMT (mean±SD) (mm) for Categories I, II, and III: 0.70±0.11, 0.81±0.16 and 0.88±0.18, respectively; mean plaque number: 0.9, 2.1 and 3, respectively). These findings were similar for Category III participants with or without DM and CKD. Conclusions: Subclinical atherosclerosis of the carotid arteries is concordant with the 10-year absolute risk of CAD and the categories in the JAS guidelines 2012.

AB - Aim: To examine whether subclinical atherosclerosis of the carotid arteries is concordant with the categories in the 2012 atherosclerosis prevention guidelines proposed by the Japan Atherosclerosis Society (JAS guidelines 2012), which adopted the estimated 10-year absolute risk of coronary artery disease (CAD) death in the NIPPON DATA80 Risk Assessment Chart. Methods: Between 2006 and 2008, 868 Japanese men 40 to 74 years of age without a history of cardiovascular disease were randomly selected from Kusatsu City, Japan. The intima media thickness (IMT) and plaque number from the common to internal carotid arteries were investigated using ultrasonography. The absolute risk of CAD death was estimated based on the individual risk factor data, and the mean IMT and plaque number in Categories I, II and III of the guidelines were examined. Results: The estimated 10-year absolute risk of CAD was directly related to the IMT (mean IMT (mean±SD) (mm) for a 10-year absolute risk of ≥2.0% and ≥5.0%: 0.88±0.18 and 0.95±0.19, respectively) and the plaque number. These results are compatible with the categories described by the guidelines (mean IMT (mean±SD) (mm) for Categories I, II, and III: 0.70±0.11, 0.81±0.16 and 0.88±0.18, respectively; mean plaque number: 0.9, 2.1 and 3, respectively). These findings were similar for Category III participants with or without DM and CKD. Conclusions: Subclinical atherosclerosis of the carotid arteries is concordant with the 10-year absolute risk of CAD and the categories in the JAS guidelines 2012.

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KW - Carotid atherosclerosis

KW - Coronary artery disease (CAD)

KW - Coronary heart disease (CHD)

KW - Intima-media thickness

KW - JAS guidelines

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