Catalytic chemoselective addition of acetonitrile to enolizable aldehydes with cationic Ru complex/DBU combination

Naoya Kumagai, Shigeki Matsunaga, Masakatsu Shibasaki

Research output: Contribution to journalArticlepeer-review

40 Citations (Scopus)

Abstract

The cooperative catalysis of CpRu(PPh3)2(CH 3CN)PF6 (1b) and DBU enables chemoselective nucleophilic activation of acetonitrile in the presence of base-sensitive aldehydes 2 to afford corresponding β-hydroxynitriles 3 in good yield.

Original languageEnglish
Pages (from-to)3600-3602
Number of pages3
JournalChemical Communications
Issue number28
DOIs
Publication statusPublished - 2005
Externally publishedYes

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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