Abstract
The reaction of t-butyldiphenylsilyl (TBDPS) chloride with secondary alcohols was catalyzed by pyrrolidinopyridine N-oxide (PPYO) in the presence of diisopropylethylamine (DIPEA) at room temperature, giving the corresponding TBDPS ethers in high yields.
Original language | English |
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Pages (from-to) | 6861-6863 |
Number of pages | 3 |
Journal | Tetrahedron Letters |
Volume | 55 |
Issue number | 50 |
DOIs | |
Publication status | Published - 2014 Dec 10 |
Keywords
- Organocatalyst
- Pyridine N-oxide
- Secondary alcohols
- Silylation
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry