Catalytic silylation of secondary alcohols by pyridine N-oxide derivative

Keisuke Yoshida, Kenichi Takao

Research output: Contribution to journal › Article

9 Citations (Scopus)

Abstract

The reaction of t-butyldiphenylsilyl (TBDPS) chloride with secondary alcohols was catalyzed by pyrrolidinopyridine N-oxide (PPYO) in the presence of diisopropylethylamine (DIPEA) at room temperature, giving the corresponding TBDPS ethers in high yields.

Original languageEnglish
Pages (from-to)6861-6863
Number of pages3
JournalTetrahedron Letters
Volume55
Issue number50
DOIs
Publication statusPublished - 2014 Dec 10

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Ethers
Oxides
Chlorides
Alcohols
Derivatives
Temperature
pyridine N-oxide

Keywords

  • Organocatalyst
  • Pyridine N-oxide
  • Secondary alcohols
  • Silylation

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Catalytic silylation of secondary alcohols by pyridine N-oxide derivative. / Yoshida, Keisuke; Takao, Kenichi.

In: Tetrahedron Letters, Vol. 55, No. 50, 10.12.2014, p. 6861-6863.

Research output: Contribution to journal › Article

Yoshida, K & Takao, K 2014, 'Catalytic silylation of secondary alcohols by pyridine N-oxide derivative', Tetrahedron Letters, vol. 55, no. 50, pp. 6861-6863. https://doi.org/10.1016/j.tetlet.2014.10.087
Yoshida K, Takao K. Catalytic silylation of secondary alcohols by pyridine N-oxide derivative. Tetrahedron Letters. 2014 Dec 10;55(50):6861-6863. https://doi.org/10.1016/j.tetlet.2014.10.087
Yoshida, Keisuke ; Takao, Kenichi. / Catalytic silylation of secondary alcohols by pyridine N-oxide derivative. In: Tetrahedron Letters. 2014 ; Vol. 55, No. 50. pp. 6861-6863.
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