Abstract
For the past few decades, spinal cord injury (SCI) has been believed to be an incurable traumatic condition, but with recent developments in stem cell biology, the field of regenerative medicine has gained hopeful momentum in the development of a treatment for this challenging pathology. Among the treatment candidates, transplantation of neural precursor cells has gained remarkable attention as a reasonable therapeutic intervention to replace the damaged central nervous system cells and promote functional recovery. Here, we highlight transplantation therapy techniques using induced pluripotent stem cells to treat SCI and review the recent research giving consideration to future clinical applications.
| Original language | English |
|---|---|
| Pages (from-to) | 75-80 |
| Number of pages | 6 |
| Journal | Regenerative Therapy |
| Volume | 11 |
| DOIs | |
| Publication status | Published - 2019 Dec 1 |
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Keywords
- Clinical application
- Induced pluripotent stem cells
- Neural precursor cells
- Spinal cord injury
ASJC Scopus subject areas
- Biomaterials
- Biomedical Engineering
- Developmental Biology
Cite this
Cell therapy for spinal cord injury using induced pluripotent stem cells. / Nagoshi, Narihito; Tsuji, Osahiko; Nakamura, Masaya; Okano, Hideyuki.
In: Regenerative Therapy, Vol. 11, 01.12.2019, p. 75-80.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Cell therapy for spinal cord injury using induced pluripotent stem cells
AU - Nagoshi, Narihito
AU - Tsuji, Osahiko
AU - Nakamura, Masaya
AU - Okano, Hideyuki
PY - 2019/12/1
Y1 - 2019/12/1
N2 - For the past few decades, spinal cord injury (SCI) has been believed to be an incurable traumatic condition, but with recent developments in stem cell biology, the field of regenerative medicine has gained hopeful momentum in the development of a treatment for this challenging pathology. Among the treatment candidates, transplantation of neural precursor cells has gained remarkable attention as a reasonable therapeutic intervention to replace the damaged central nervous system cells and promote functional recovery. Here, we highlight transplantation therapy techniques using induced pluripotent stem cells to treat SCI and review the recent research giving consideration to future clinical applications.
AB - For the past few decades, spinal cord injury (SCI) has been believed to be an incurable traumatic condition, but with recent developments in stem cell biology, the field of regenerative medicine has gained hopeful momentum in the development of a treatment for this challenging pathology. Among the treatment candidates, transplantation of neural precursor cells has gained remarkable attention as a reasonable therapeutic intervention to replace the damaged central nervous system cells and promote functional recovery. Here, we highlight transplantation therapy techniques using induced pluripotent stem cells to treat SCI and review the recent research giving consideration to future clinical applications.
KW - Clinical application
KW - Induced pluripotent stem cells
KW - Neural precursor cells
KW - Spinal cord injury
UR - http://www.scopus.com/inward/record.url?scp=85067085180&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85067085180&partnerID=8YFLogxK
U2 - 10.1016/j.reth.2019.05.006
DO - 10.1016/j.reth.2019.05.006
M3 - Review article
AN - SCOPUS:85067085180
VL - 11
SP - 75
EP - 80
JO - Regenerative Therapy
JF - Regenerative Therapy
SN - 2352-3204
ER -