Cell therapy for spinal cord injury using induced pluripotent stem cells

Research output: Contribution to journalReview article

Abstract

For the past few decades, spinal cord injury (SCI) has been believed to be an incurable traumatic condition, but with recent developments in stem cell biology, the field of regenerative medicine has gained hopeful momentum in the development of a treatment for this challenging pathology. Among the treatment candidates, transplantation of neural precursor cells has gained remarkable attention as a reasonable therapeutic intervention to replace the damaged central nervous system cells and promote functional recovery. Here, we highlight transplantation therapy techniques using induced pluripotent stem cells to treat SCI and review the recent research giving consideration to future clinical applications.

Original languageEnglish
Pages (from-to)75-80
Number of pages6
JournalRegenerative Therapy
Volume11
DOIs
Publication statusPublished - 2019 Dec 1

Fingerprint

Induced Pluripotent Stem Cells
Cell- and Tissue-Based Therapy
Stem cells
Spinal Cord Injuries
Cytology
Neurology
Pathology
Momentum
Transplantation
Recovery
Regenerative Medicine
Therapeutics
Cell Biology
Stem Cells
Central Nervous System
Research

Keywords

  • Clinical application
  • Induced pluripotent stem cells
  • Neural precursor cells
  • Spinal cord injury

ASJC Scopus subject areas

  • Biomaterials
  • Biomedical Engineering
  • Developmental Biology

Cite this

Cell therapy for spinal cord injury using induced pluripotent stem cells. / Nagoshi, Narihito; Tsuji, Osahiko; Nakamura, Masaya; Okano, Hideyuki.

In: Regenerative Therapy, Vol. 11, 01.12.2019, p. 75-80.

Research output: Contribution to journalReview article

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