Cellophane-based analytical devices for pump-free liquid transport and background-tinted colorimetric assays

Hiroki Shigemori, Kento Maejima, Hiroyuki Shibata, Yuki Hiruta, Daniel Citterio

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

This report suggests utilizing “cellophane” as a new substrate material for point-of-care testing (POCT) devices. Cellophane-based microfluidic devices were fabricated by a print, cut and lamination (PCL) methodology and sample liquid was transported into four assay areas without external pumping. Furthermore, making use of the transparency of cellophane, background-tinted devices were fabricated. Based on a blue background-tinted cellophane device, the dynamic range of a hue-based H2O2 assay was 46-fold increased compared to performing the same assay on a white background device. Finally, turbidity testing for albumin was implemented on black background-tinted devices with a visual detection limit of 15 mg/dL.

Original languageEnglish
Title of host publicationMicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PublisherChemical and Biological Microsystems Society
Pages422-423
Number of pages2
ISBN (Electronic)9781733419017
Publication statusPublished - 2020
Event24th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2020 - Virtual, Online
Duration: 2020 Oct 42020 Oct 9

Publication series

NameMicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Conference

Conference24th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2020
CityVirtual, Online
Period20/10/420/10/9

Keywords

  • Cellophane
  • Colorimetric analysis
  • Microfluidic device
  • POCT
  • Turbidity testing

ASJC Scopus subject areas

  • Chemical Engineering (miscellaneous)
  • Bioengineering
  • Chemistry(all)
  • Control and Systems Engineering

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