Cellular uptake and saccharide chain elongation of "fluoro- amphiphilic" glycosides

Maria Carmelita Z. Kasuya; Ayaka Ito; Reuben Cusi; Toshinori Sato; Kenichi Hatanaka

doi:10.1246/cl.2005.856

Cellular uptake and saccharide chain elongation of "fluoro- amphiphilic" glycosides

Maria Carmelita Z. Kasuya, Ayaka Ito, Reuben Cusi, Toshinori Sato, Kenichi Hatanaka

Department of Biosciences and Informatics

Research output: Contribution to journal › Article › peer-review

16 Citations (Scopus)

Abstract

"Fluoro-amphiphilic" glycosides are practical alternatives for the preparation of oligosaccharides. Fluoro-amphiphilic saccharide primers possessing a hydrophilic sugar moiety and a fluorous tag could be taken up by cells and elongated by cellular enzymes. The elongated products were released by cells to the culture medium and could be easily separated from other components by simple extraction with a fluorous solvent.

Original language	English
Pages (from-to)	856-857
Number of pages	2
Journal	Chemistry Letters
Volume	34
Issue number	6
DOIs	https://doi.org/10.1246/cl.2005.856
Publication status	Published - 2005 Jun 5

ASJC Scopus subject areas

Chemistry(all)

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10.1246/cl.2005.856

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AU - Ito, Ayaka

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AU - Hatanaka, Kenichi

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AB - "Fluoro-amphiphilic" glycosides are practical alternatives for the preparation of oligosaccharides. Fluoro-amphiphilic saccharide primers possessing a hydrophilic sugar moiety and a fluorous tag could be taken up by cells and elongated by cellular enzymes. The elongated products were released by cells to the culture medium and could be easily separated from other components by simple extraction with a fluorous solvent.

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Cellular uptake and saccharide chain elongation of "fluoro- amphiphilic" glycosides

Abstract

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