Changes in cerebro-cerebellar interaction during response inhibition after performance improvement

Satoshi Hirose, Koji Jimura, Akira Kunimatsu, Osamu Abe, Kuni Ohtomo, Yasushi Miyashita, Seiki Konishi

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

It has been demonstrated that motor learning is supported by the cerebellum and the cerebro-cerebellar interaction. Response inhibition involves motor responses and the higher-order inhibition that controls the motor responses. In this functional MRI study, we measured the cerebro-cerebellar interaction during response inhibition in two separate days of task performance, and detected the changes in the interaction following performance improvement. Behaviorally, performance improved in the second day, compared to the first day. The psycho-physiological interaction (PPI) analysis revealed the interaction decrease from the right inferior frontal cortex (rIFC) to the cerebellum (lobule VII or VI). It was also revealed that the interaction increased from the same cerebellar region to the primary motor area. These results suggest the involvement of the cerebellum in response inhibition, and raise the possibility that the performance improvement was supported by the changes in the cerebro-cerebellar interaction.

Original languageEnglish
Pages (from-to)142-148
Number of pages7
JournalNeuroImage
Volume99
DOIs
Publication statusPublished - 2014 Oct 1
Externally publishedYes

Fingerprint

Cerebellum
Motor Cortex
Task Performance and Analysis
Frontal Lobe
Magnetic Resonance Imaging
Learning
Inhibition (Psychology)

Keywords

  • Go/no-go task
  • Human

ASJC Scopus subject areas

  • Cognitive Neuroscience
  • Neurology
  • Medicine(all)

Cite this

Changes in cerebro-cerebellar interaction during response inhibition after performance improvement. / Hirose, Satoshi; Jimura, Koji; Kunimatsu, Akira; Abe, Osamu; Ohtomo, Kuni; Miyashita, Yasushi; Konishi, Seiki.

In: NeuroImage, Vol. 99, 01.10.2014, p. 142-148.

Research output: Contribution to journalArticle

Hirose, Satoshi ; Jimura, Koji ; Kunimatsu, Akira ; Abe, Osamu ; Ohtomo, Kuni ; Miyashita, Yasushi ; Konishi, Seiki. / Changes in cerebro-cerebellar interaction during response inhibition after performance improvement. In: NeuroImage. 2014 ; Vol. 99. pp. 142-148.
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