Changes in corneal sensation, epithelial damage, and tear function after descemet stripping automated endothelial keratoplasty

Yumiko Hirayama, Yoshiyuki Satake, Masatoshi Hirayama, Seika Shimazaki-Den, Kenji Konomi, Jun Shimazaki

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)

Abstract

Purpose: To study the ocular surface changes in eyes after Descemet stripping automated endothelial keratoplasty (DSAEK) compared with those after penetrating keratoplasty (PKP). Methods: This prospective study compared the changes in 31 eyes of 28 patients who underwent DSAEK (DSAEK group) with those in 15 disease-matched eyes of 15 patients who underwent PKP (PKP group). Corneal epithelial integrity was evaluated using a fluorescein staining score. Corneal sensation was measured with a Cochet-Bonnet esthesiometer. Tear function was evaluated using the Schirmer test, tear clearance test, tear function index, and tear break-up time. Results: The postoperative fluorescein staining score was significantly higher in the PKP group than in the DSAEK group (P = 0.02). Postoperative corneal sensation was significantly better in the DSAEK group than in the PKP group (P < 0.01). Corneal sensation after DSAEK was significantly better than the preoperative value (P = 0.02). There were no statistically significant changes in the Schirmer test, tear clearance test, tear function index, or break-up time before and after the surgery in both the DSAEK and PKP groups. No significant differences were observed between the DSAEK and PKP groups after the surgery. Conclusions: Corneal sensation was preserved, and epithelial damage was less severe after DSAEK compared with PKP. Preservation of corneal sensation may contribute to the early recovery of visual function and long-term maintenance of ocular surface health after DSAEK.

Original languageEnglish
Pages (from-to)1255-1259
Number of pages5
JournalCornea
Volume32
Issue number9
DOIs
Publication statusPublished - 2013 Sep

Keywords

  • corneal epithelium
  • corneal sensation
  • DSAEK
  • tears

ASJC Scopus subject areas

  • Ophthalmology

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