TY - JOUR
T1 - Changes in metabolic parameters following a switch to aripiprazole in Japanese patients with schizophrenia
T2 - One-year follow-up study
AU - Takeuchi, Hiroyoshi
AU - Uchida, Hiroyuki
AU - Suzuki, Takefumi
AU - Watanabe, Koichiro
AU - Kashima, Haruo
PY - 2010/2/1
Y1 - 2010/2/1
N2 - The purpose of the present study was to evaluate changes in metabolic parameters after switching to aripiprazole in Japanese population. In this 1-year observation study, following a switch to aripiprazole, 32 patients with schizophrenia were observed and assessment was done of bodyweight, total cholesterol, triglyceride, serum prolactin level, and corrected QT (QTc) interval. Significant reductions were observed in these parameters other than QTc interval. Given known detrimental metabolic and hormonal effects of some atypical antipsychotics, a switch to aripiprazole may warrant serious consideration also in Asian patients who suffer those side-effects.
AB - The purpose of the present study was to evaluate changes in metabolic parameters after switching to aripiprazole in Japanese population. In this 1-year observation study, following a switch to aripiprazole, 32 patients with schizophrenia were observed and assessment was done of bodyweight, total cholesterol, triglyceride, serum prolactin level, and corrected QT (QTc) interval. Significant reductions were observed in these parameters other than QTc interval. Given known detrimental metabolic and hormonal effects of some atypical antipsychotics, a switch to aripiprazole may warrant serious consideration also in Asian patients who suffer those side-effects.
KW - Antipsychotics
KW - Aripiprazole
KW - Metabolic
KW - Side-effect
UR - http://www.scopus.com/inward/record.url?scp=75649110751&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=75649110751&partnerID=8YFLogxK
U2 - 10.1111/j.1440-1819.2009.02036.x
DO - 10.1111/j.1440-1819.2009.02036.x
M3 - Article
C2 - 19968829
AN - SCOPUS:75649110751
SN - 1323-1316
VL - 64
SP - 104
EP - 106
JO - Psychiatry and Clinical Neurosciences
JF - Psychiatry and Clinical Neurosciences
IS - 1
ER -
