Changes of cervical spinal cord and cervical spinal canal with age in asymptomatic subjects

M. Ishikawa, Morio Matsumoto, Y. Fujimura, K. Chiba, Y. Toyama

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

Study design: Prospective study on magnetic resonance imaging (MRI) and radiographic findings of the cervical spine. Objective: To elucidate the age-related changes of the cervical spinal cord and the cervical spinal canal and the relationship between the spinal cord and the spinal canal in asymptomatic subjects using MRI and radiography. Setting: Tokyo, Japan. Methods: The transverse area of the cervical spinal cord and the ratio of the anteroposterior diameter to the transverse diameter (RAPT) were investigated, using MRI in 229 asymptomatic subjects. The sagittal spinal canal diameter and anteroposterior diameter of the cervical vertebral body were also measured on plain lateral radiographs. The canal body ratio (CBR), which was defined as the diameter of the spinal canal divided by that of the vertebral body, was calculated. Results: The transverse spinal cord area correlated negatively with age. RAPT did not correlate with age. The CBR correlated negatively with age. The correlation between spinal cord area and CBR was significant but weak and the correlation between RAPT and CBR was not significant. Conclusion: The transverse area of the cervical spinal cord measured by MRI decreased with age, while RAPT remained unchanged. The bony spinal canal became narrower with age. The spinal cord area and the shapes of the spinal cord were independent from the spinal canal diameter in asymptomatic subjects. These facts should be considered when evaluating radiological findings in patients with cervical spinal disorders.

Original languageEnglish
Pages (from-to)159-163
Number of pages5
JournalSpinal Cord
Volume41
Issue number3
DOIs
Publication statusPublished - 2003 Mar 1

Fingerprint

Spinal Canal
Spinal Cord
Magnetic Resonance Imaging
Tokyo
Cervical Cord
Radiography
Japan
Spine
Prospective Studies

Keywords

  • Aging
  • Asymptomatic subject
  • Cervical spinal canal
  • Cervical spinal cord
  • MR imaging
  • Radiography

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Changes of cervical spinal cord and cervical spinal canal with age in asymptomatic subjects. / Ishikawa, M.; Matsumoto, Morio; Fujimura, Y.; Chiba, K.; Toyama, Y.

In: Spinal Cord, Vol. 41, No. 3, 01.03.2003, p. 159-163.

Research output: Contribution to journalArticle

Ishikawa, M. ; Matsumoto, Morio ; Fujimura, Y. ; Chiba, K. ; Toyama, Y. / Changes of cervical spinal cord and cervical spinal canal with age in asymptomatic subjects. In: Spinal Cord. 2003 ; Vol. 41, No. 3. pp. 159-163.
@article{bb9e4648596140e992e015a5159d9f7f,
title = "Changes of cervical spinal cord and cervical spinal canal with age in asymptomatic subjects",
abstract = "Study design: Prospective study on magnetic resonance imaging (MRI) and radiographic findings of the cervical spine. Objective: To elucidate the age-related changes of the cervical spinal cord and the cervical spinal canal and the relationship between the spinal cord and the spinal canal in asymptomatic subjects using MRI and radiography. Setting: Tokyo, Japan. Methods: The transverse area of the cervical spinal cord and the ratio of the anteroposterior diameter to the transverse diameter (RAPT) were investigated, using MRI in 229 asymptomatic subjects. The sagittal spinal canal diameter and anteroposterior diameter of the cervical vertebral body were also measured on plain lateral radiographs. The canal body ratio (CBR), which was defined as the diameter of the spinal canal divided by that of the vertebral body, was calculated. Results: The transverse spinal cord area correlated negatively with age. RAPT did not correlate with age. The CBR correlated negatively with age. The correlation between spinal cord area and CBR was significant but weak and the correlation between RAPT and CBR was not significant. Conclusion: The transverse area of the cervical spinal cord measured by MRI decreased with age, while RAPT remained unchanged. The bony spinal canal became narrower with age. The spinal cord area and the shapes of the spinal cord were independent from the spinal canal diameter in asymptomatic subjects. These facts should be considered when evaluating radiological findings in patients with cervical spinal disorders.",
keywords = "Aging, Asymptomatic subject, Cervical spinal canal, Cervical spinal cord, MR imaging, Radiography",
author = "M. Ishikawa and Morio Matsumoto and Y. Fujimura and K. Chiba and Y. Toyama",
year = "2003",
month = "3",
day = "1",
doi = "10.1038/sj.sc.3101375",
language = "English",
volume = "41",
pages = "159--163",
journal = "Spinal Cord",
issn = "1362-4393",
publisher = "Nature Publishing Group",
number = "3",

}

TY - JOUR

T1 - Changes of cervical spinal cord and cervical spinal canal with age in asymptomatic subjects

AU - Ishikawa, M.

AU - Matsumoto, Morio

AU - Fujimura, Y.

AU - Chiba, K.

AU - Toyama, Y.

PY - 2003/3/1

Y1 - 2003/3/1

N2 - Study design: Prospective study on magnetic resonance imaging (MRI) and radiographic findings of the cervical spine. Objective: To elucidate the age-related changes of the cervical spinal cord and the cervical spinal canal and the relationship between the spinal cord and the spinal canal in asymptomatic subjects using MRI and radiography. Setting: Tokyo, Japan. Methods: The transverse area of the cervical spinal cord and the ratio of the anteroposterior diameter to the transverse diameter (RAPT) were investigated, using MRI in 229 asymptomatic subjects. The sagittal spinal canal diameter and anteroposterior diameter of the cervical vertebral body were also measured on plain lateral radiographs. The canal body ratio (CBR), which was defined as the diameter of the spinal canal divided by that of the vertebral body, was calculated. Results: The transverse spinal cord area correlated negatively with age. RAPT did not correlate with age. The CBR correlated negatively with age. The correlation between spinal cord area and CBR was significant but weak and the correlation between RAPT and CBR was not significant. Conclusion: The transverse area of the cervical spinal cord measured by MRI decreased with age, while RAPT remained unchanged. The bony spinal canal became narrower with age. The spinal cord area and the shapes of the spinal cord were independent from the spinal canal diameter in asymptomatic subjects. These facts should be considered when evaluating radiological findings in patients with cervical spinal disorders.

AB - Study design: Prospective study on magnetic resonance imaging (MRI) and radiographic findings of the cervical spine. Objective: To elucidate the age-related changes of the cervical spinal cord and the cervical spinal canal and the relationship between the spinal cord and the spinal canal in asymptomatic subjects using MRI and radiography. Setting: Tokyo, Japan. Methods: The transverse area of the cervical spinal cord and the ratio of the anteroposterior diameter to the transverse diameter (RAPT) were investigated, using MRI in 229 asymptomatic subjects. The sagittal spinal canal diameter and anteroposterior diameter of the cervical vertebral body were also measured on plain lateral radiographs. The canal body ratio (CBR), which was defined as the diameter of the spinal canal divided by that of the vertebral body, was calculated. Results: The transverse spinal cord area correlated negatively with age. RAPT did not correlate with age. The CBR correlated negatively with age. The correlation between spinal cord area and CBR was significant but weak and the correlation between RAPT and CBR was not significant. Conclusion: The transverse area of the cervical spinal cord measured by MRI decreased with age, while RAPT remained unchanged. The bony spinal canal became narrower with age. The spinal cord area and the shapes of the spinal cord were independent from the spinal canal diameter in asymptomatic subjects. These facts should be considered when evaluating radiological findings in patients with cervical spinal disorders.

KW - Aging

KW - Asymptomatic subject

KW - Cervical spinal canal

KW - Cervical spinal cord

KW - MR imaging

KW - Radiography

UR - http://www.scopus.com/inward/record.url?scp=0037343402&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0037343402&partnerID=8YFLogxK

U2 - 10.1038/sj.sc.3101375

DO - 10.1038/sj.sc.3101375

M3 - Article

C2 - 12612618

AN - SCOPUS:0037343402

VL - 41

SP - 159

EP - 163

JO - Spinal Cord

JF - Spinal Cord

SN - 1362-4393

IS - 3

ER -