Characteristics and risk factors for type 2 endoleak in an east asian population from a Japanese multicenter database

Naoki Fujimura, Hideaki Obara, Kentaro Matsubara, Susumu Watada, Shintaro Shibutani, Takurin Akiyoshi, Hirohisa Harada, Yuko Kitagawa

Research output: Contribution to journalArticlepeer-review

12 Citations (Scopus)


Background: Clinically distinct differences exist between East Asian and Caucasian subjects, but data for type 2 endoleak (T2EL) are limited in the East Asian population. The aim of this study was to analyze the characteristics of East Asian T2EL using a Japanese multicenter database. Methods and Results: Retrospective analysis of 832 endovascular aneurysm repairs performed from 2008 to 2014 were conducted. T2EL was observed in 234 cases (28.1%), and in 32 cases (3.8%) it led to sac expansion >5 mm caused by isolated T2EL (median follow-up, 35.6 months). On univariate and multivariate analysis, non-smoker status (odds ratio [OR], 2.216; P<0.001), Excluder stent graft (OR, 2.027; P<0.001), and T2EL at final angiogram (OR, 2.080; P<0.001) were risk factors for T2EL. On multivariate analysis for isolated T2EL with sac expansion, only non-smoker status remained (OR, 2.671; P<0.001). Other than T1EL, isolated T2EL was the most significant risk factor for sac expansion (OR, 18.486; P<0.001). Furthermore, out of 11 transarterial embolization procedures initiated, 4 led to rupture during follow-up. Conclusions: East Asian T2EL had a strong relationship with non-smoker status. Also, T2EL was a significant risk factor for sac expansion, which sometimes led to rupture even after intervention. Along with the high prevalence of T2EL observed, East Asian T2EL may not always be benign.

Original languageEnglish
Pages (from-to)118-123
Number of pages6
JournalCirculation Journal
Issue number1
Publication statusPublished - 2015 Dec 25


  • East asian
  • Endovascular aneurysm repair
  • Smoking
  • Type 2 endoleak

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


Dive into the research topics of 'Characteristics and risk factors for type 2 endoleak in an east asian population from a Japanese multicenter database'. Together they form a unique fingerprint.

Cite this