Characteristics of gastric cancer detected within 1 year after successful eradication of Helicobacter pylori

Toshihiro Nishizawa, Hidekazu Suzuki, Toru Arano, Shuntaro Yoshida, Hiroharu Yamashita, Keisuke Hata, Takanori Kanai, Naohisa Yahagi, Osamu Toyoshima

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Gastric cancers are sometimes diagnosed in patients who have successfully undergone Helicobacter pylori (H. pylori) eradication. We analyzed the clinicopathological features of gastric cancers detected after eradication to clarify their characteristics. We reviewed 31 patients with 34 cases of gastric cancer detected after successful H. pylori eradication. Clinicopathological characteristics analyzed included interval since eradication, interval since last endoscopy, tumor size, and depth of invasion. Patients were classified into two groups: early detection (<1 year since eradication) and delayed detection (≥1 year since eradication). The interval since last endoscopy was significantly shorter in the early detection group than in the delayed detection group. However, gastric cancers were significantly larger and more invasive in the early detection group than in the delayed detection group. In conclusion, diligent endoscopy is necessary during the first year after successful H. pylori eradication.

Original languageEnglish
Pages (from-to)226-230
Number of pages5
JournalJournal of Clinical Biochemistry and Nutrition
Volume59
Issue number3
DOIs
Publication statusPublished - 2016

Keywords

  • Eradication
  • Gastric cancer
  • H. pylori

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics
  • Clinical Biochemistry

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