Chemical approach for target-selective degradation of oligosaccharides using photoactivatable organic molecules

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2 Citations (Scopus)

Abstract

Molecular design, chemical synthesis, and biological evaluation of several organic molecules, which can target-selectively photodegrade oligosaccharides by irradiation with a specific wavelength of light under mild conditions without any additives, are introduced. These novel class of photochemical agents promise bright prospects for finding not only molecular-targeted bioprobes for understanding of the structure-activity relationships of oligosaccharides but also novel therapeutic drugs targeting biologically important oligosaccharides.

Original languageEnglish
Pages (from-to)475-482
Number of pages8
JournalGlycoconjugate Journal
Volume32
Issue number7
DOIs
Publication statusPublished - 2015 Apr 28

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Keywords

  • Anthracene
  • Anthraquinone
  • Boronic acid
  • Kemp's acid
  • Lectin
  • Photodegradation

ASJC Scopus subject areas

  • Biochemistry
  • Cell Biology
  • Molecular Biology

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