Chemical methods for degradation of target oligosaccharides using designed light-activatable organic molecules

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6 Citations (Scopus)

Abstract

Carbohydrates play crucial roles in a wide range of biological processes, including serious diseases. The development of novel and innovative methods for selective control of specific oligosaccharide functions has attracted much attention in the fields of chemistry, biology, and medicine. In this feature article, the development of novel chemical tools, which can degrade target oligosaccharides by irradiation with a specific wavelength of light under mild conditions without any additives, is introduced. This novel class of photochemical agents promise bright prospects for finding not only molecular-targeted bioprobes for understanding of the structure-activity relationships of oligosaccharides but also novel therapeutic drugs targeting oligosaccharides.

Original languageEnglish
Pages (from-to)4397-4407
Number of pages11
JournalChemical Communications
Volume48
Issue number37
DOIs
Publication statusPublished - 2012 May 11

Fingerprint

Oligosaccharides
Degradation
Molecules
Carbohydrates
Medicine
Irradiation
Wavelength

ASJC Scopus subject areas

  • Metals and Alloys
  • Materials Chemistry
  • Surfaces, Coatings and Films
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Catalysis
  • Chemistry(all)

Cite this

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