Chemical screening for single bacterial activity using bacteria immobilization into microporous

Tomonori Kano, Tomomi Inaba, Kazuhiko Higashi, Norihisa Miki

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In this paper we demonstrate chemical screening using a microbial micro reactor immobilizing microbes by dielectrophoresis into micro holes, as shown in Fig.1. The flow-type microbial micro reactor facilitates collecting and evaluating reaction products while immobilization of microbes enables quantification of the number of microbes involved in the reaction and making their reactions conditions consistent. We applied this system to investigate the effects of chemicals on microbial activities of Corynebacterium glutamicum, which is widely used to produce beneficial chemicals in industry. The proposed system will be of great help to reduce the time and cost to find optimum biochemical microbial reactions.

Original languageEnglish
Title of host publicationProceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012
PublisherChemical and Biological Microsystems Society
Pages1201-1203
Number of pages3
ISBN (Print)9780979806452
Publication statusPublished - 2012 Jan 1
Event16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012 - Okinawa, Japan
Duration: 2012 Oct 282012 Nov 1

Publication series

NameProceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012

Other

Other16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012
CountryJapan
CityOkinawa
Period12/10/2812/11/1

Keywords

  • Bacteria
  • Chemical screening
  • Dielectrophoresis
  • Immobilization
  • Micro reactor

ASJC Scopus subject areas

  • Chemical Engineering (miscellaneous)
  • Bioengineering

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  • Cite this

    Kano, T., Inaba, T., Higashi, K., & Miki, N. (2012). Chemical screening for single bacterial activity using bacteria immobilization into microporous. In Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012 (pp. 1201-1203). (Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012). Chemical and Biological Microsystems Society.