Chemical transformation of embelin through dimerization during preparation of a decoction

Fumiyuki Kiuchi, Noriko Suzuki, Yumiko Fukumoto, Yoshihisa Goto, Mariko Mitsui, Yoshisuke Tsuda

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Embelin, a major constituent of Embelia ribes BURM. (Myrsinaceae) was transformed into different types of compounds through dimerization during preparation of a decoction. Two of the products are proposed to have furanylidene benzofuranone and 1,4-dibenzofurandione skeletons on the basis of spectroscopic means. The transformation of embelin in boiling water is markedly accelerated by the presence of fatty acids.

Original languageEnglish
Pages (from-to)1225-1128
Number of pages98
JournalChemical and Pharmaceutical Bulletin
Volume46
Issue number8
Publication statusPublished - 1998
Externally publishedYes

Fingerprint

Dimerization
Embelia
Myrsinaceae
Ribes
Skeleton
Boiling liquids
Fatty Acids
Water
embelin

Keywords

  • 1,4-dibenzofurandione
  • Decoction
  • Dimerization
  • Embelia ribes
  • Embelin
  • Furanylidene benzofuranone

ASJC Scopus subject areas

  • Chemistry(all)
  • Organic Chemistry
  • Drug Discovery
  • Pharmacology

Cite this

Kiuchi, F., Suzuki, N., Fukumoto, Y., Goto, Y., Mitsui, M., & Tsuda, Y. (1998). Chemical transformation of embelin through dimerization during preparation of a decoction. Chemical and Pharmaceutical Bulletin, 46(8), 1225-1128.

Chemical transformation of embelin through dimerization during preparation of a decoction. / Kiuchi, Fumiyuki; Suzuki, Noriko; Fukumoto, Yumiko; Goto, Yoshihisa; Mitsui, Mariko; Tsuda, Yoshisuke.

In: Chemical and Pharmaceutical Bulletin, Vol. 46, No. 8, 1998, p. 1225-1128.

Research output: Contribution to journalArticle

Kiuchi, F, Suzuki, N, Fukumoto, Y, Goto, Y, Mitsui, M & Tsuda, Y 1998, 'Chemical transformation of embelin through dimerization during preparation of a decoction', Chemical and Pharmaceutical Bulletin, vol. 46, no. 8, pp. 1225-1128.
Kiuchi, Fumiyuki ; Suzuki, Noriko ; Fukumoto, Yumiko ; Goto, Yoshihisa ; Mitsui, Mariko ; Tsuda, Yoshisuke. / Chemical transformation of embelin through dimerization during preparation of a decoction. In: Chemical and Pharmaceutical Bulletin. 1998 ; Vol. 46, No. 8. pp. 1225-1128.
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