Chemical transformation of embelin through dimerization during preparation of a decoction

Fumiyuki Kiuchi, Noriko Suzuki, Yumiko Fukumoto, Yoshihisa Goto, Mariko Mitsui, Yoshisuke Tsuda

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Embelin, a major constituent of Embelia ribes BURM. (Myrsinaceae) was transformed into different types of compounds through dimerization during preparation of a decoction. Two of the products are proposed to have furanylidene benzofuranone and 1,4-dibenzofurandione skeletons on the basis of spectroscopic means. The transformation of embelin in boiling water is markedly accelerated by the presence of fatty acids.

Original languageEnglish
Pages (from-to)1225-1128
Number of pages98
JournalChemical and Pharmaceutical Bulletin
Volume46
Issue number8
DOIs
Publication statusPublished - 1998 Jan 1
Externally publishedYes

Keywords

  • 1,4-dibenzofurandione
  • Decoction
  • Dimerization
  • Embelia ribes
  • Embelin
  • Furanylidene benzofuranone

ASJC Scopus subject areas

  • Chemistry(all)
  • Drug Discovery

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