Childhood bacterial meningitis trends in Japan from 2005 to 2006

Keisuke Sunakawa, Kimiko Ubukata, Nahoko Chiba, Keiko Hasegawa, Masato Nonoyama, Satoshi Iwata, Hironobu Akita, Yoshitake Sato

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

We surveyed pediatric bacterial meningitis epidemiology from January 2005 to December 2006 in Japan, with the following results. Bacterial meningitis cases numbered 246 -138 boys and 108 girls-, equivalent to 1.7-1.72 children of 1,000 hospitalized in pediatrics per year. The age distribution for infection was highest in those under 1 year of age and decreased with increasing age, Haemophilus influenzae was the most common infection causing the pathogen, followed by Streptococcus pneumoniae, group B streptococcus, and Escherichia coli. The relationship between causative pathogens and age distribution was as follows: group B streptococcus and E. coli were major pathogens in patients under 4 months old and H. influenzae and S. pneumoniae in those over 4 months old. Susceptibility tests at individual facilities showed 59.3% of H. influen- zae isolates and 69.3% of S. pneumoniae isolates in 2004 to be drug-resistant. Ampicillin and cephem antibiotics are effective against GBS, E. coli, and Listeria, so combined of ampicillin and cephem antibiotics are used as first-line antibiotics in many facilities in patients under 4 month old and combined of carbapenem antibiotics effective against PRSP and cephem effective against H. influenzae were the first choice against childhood bacterial meningitis in patients over 4 month old.

Original languageEnglish
Pages (from-to)187-197
Number of pages11
JournalKansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases
Volume82
Issue number3
Publication statusPublished - 2008 May
Externally publishedYes

Fingerprint

Bacterial Meningitides
Haemophilus influenzae
Streptococcus pneumoniae
Japan
Streptococcus agalactiae
Age Distribution
Ampicillin
Escherichia coli
Anti-Bacterial Agents
Pediatrics
Listeria
Carbapenems
Infection
Streptococcus
Human Influenza
Epidemiology
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Sunakawa, K., Ubukata, K., Chiba, N., Hasegawa, K., Nonoyama, M., Iwata, S., ... Sato, Y. (2008). Childhood bacterial meningitis trends in Japan from 2005 to 2006. Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 82(3), 187-197.

Childhood bacterial meningitis trends in Japan from 2005 to 2006. / Sunakawa, Keisuke; Ubukata, Kimiko; Chiba, Nahoko; Hasegawa, Keiko; Nonoyama, Masato; Iwata, Satoshi; Akita, Hironobu; Sato, Yoshitake.

In: Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, Vol. 82, No. 3, 05.2008, p. 187-197.

Research output: Contribution to journalArticle

Sunakawa, K, Ubukata, K, Chiba, N, Hasegawa, K, Nonoyama, M, Iwata, S, Akita, H & Sato, Y 2008, 'Childhood bacterial meningitis trends in Japan from 2005 to 2006', Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, vol. 82, no. 3, pp. 187-197.
Sunakawa, Keisuke ; Ubukata, Kimiko ; Chiba, Nahoko ; Hasegawa, Keiko ; Nonoyama, Masato ; Iwata, Satoshi ; Akita, Hironobu ; Sato, Yoshitake. / Childhood bacterial meningitis trends in Japan from 2005 to 2006. In: Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases. 2008 ; Vol. 82, No. 3. pp. 187-197.
@article{31cd35370a2e474eb49907aea7494b80,
title = "Childhood bacterial meningitis trends in Japan from 2005 to 2006",
abstract = "We surveyed pediatric bacterial meningitis epidemiology from January 2005 to December 2006 in Japan, with the following results. Bacterial meningitis cases numbered 246 -138 boys and 108 girls-, equivalent to 1.7-1.72 children of 1,000 hospitalized in pediatrics per year. The age distribution for infection was highest in those under 1 year of age and decreased with increasing age, Haemophilus influenzae was the most common infection causing the pathogen, followed by Streptococcus pneumoniae, group B streptococcus, and Escherichia coli. The relationship between causative pathogens and age distribution was as follows: group B streptococcus and E. coli were major pathogens in patients under 4 months old and H. influenzae and S. pneumoniae in those over 4 months old. Susceptibility tests at individual facilities showed 59.3{\%} of H. influen- zae isolates and 69.3{\%} of S. pneumoniae isolates in 2004 to be drug-resistant. Ampicillin and cephem antibiotics are effective against GBS, E. coli, and Listeria, so combined of ampicillin and cephem antibiotics are used as first-line antibiotics in many facilities in patients under 4 month old and combined of carbapenem antibiotics effective against PRSP and cephem effective against H. influenzae were the first choice against childhood bacterial meningitis in patients over 4 month old.",
author = "Keisuke Sunakawa and Kimiko Ubukata and Nahoko Chiba and Keiko Hasegawa and Masato Nonoyama and Satoshi Iwata and Hironobu Akita and Yoshitake Sato",
year = "2008",
month = "5",
language = "English",
volume = "82",
pages = "187--197",
journal = "Nippon Densenbyo Gakkai zasshi",
issn = "0387-5911",
publisher = "Nihon Kansensho Gakkai",
number = "3",

}

TY - JOUR

T1 - Childhood bacterial meningitis trends in Japan from 2005 to 2006

AU - Sunakawa, Keisuke

AU - Ubukata, Kimiko

AU - Chiba, Nahoko

AU - Hasegawa, Keiko

AU - Nonoyama, Masato

AU - Iwata, Satoshi

AU - Akita, Hironobu

AU - Sato, Yoshitake

PY - 2008/5

Y1 - 2008/5

N2 - We surveyed pediatric bacterial meningitis epidemiology from January 2005 to December 2006 in Japan, with the following results. Bacterial meningitis cases numbered 246 -138 boys and 108 girls-, equivalent to 1.7-1.72 children of 1,000 hospitalized in pediatrics per year. The age distribution for infection was highest in those under 1 year of age and decreased with increasing age, Haemophilus influenzae was the most common infection causing the pathogen, followed by Streptococcus pneumoniae, group B streptococcus, and Escherichia coli. The relationship between causative pathogens and age distribution was as follows: group B streptococcus and E. coli were major pathogens in patients under 4 months old and H. influenzae and S. pneumoniae in those over 4 months old. Susceptibility tests at individual facilities showed 59.3% of H. influen- zae isolates and 69.3% of S. pneumoniae isolates in 2004 to be drug-resistant. Ampicillin and cephem antibiotics are effective against GBS, E. coli, and Listeria, so combined of ampicillin and cephem antibiotics are used as first-line antibiotics in many facilities in patients under 4 month old and combined of carbapenem antibiotics effective against PRSP and cephem effective against H. influenzae were the first choice against childhood bacterial meningitis in patients over 4 month old.

AB - We surveyed pediatric bacterial meningitis epidemiology from January 2005 to December 2006 in Japan, with the following results. Bacterial meningitis cases numbered 246 -138 boys and 108 girls-, equivalent to 1.7-1.72 children of 1,000 hospitalized in pediatrics per year. The age distribution for infection was highest in those under 1 year of age and decreased with increasing age, Haemophilus influenzae was the most common infection causing the pathogen, followed by Streptococcus pneumoniae, group B streptococcus, and Escherichia coli. The relationship between causative pathogens and age distribution was as follows: group B streptococcus and E. coli were major pathogens in patients under 4 months old and H. influenzae and S. pneumoniae in those over 4 months old. Susceptibility tests at individual facilities showed 59.3% of H. influen- zae isolates and 69.3% of S. pneumoniae isolates in 2004 to be drug-resistant. Ampicillin and cephem antibiotics are effective against GBS, E. coli, and Listeria, so combined of ampicillin and cephem antibiotics are used as first-line antibiotics in many facilities in patients under 4 month old and combined of carbapenem antibiotics effective against PRSP and cephem effective against H. influenzae were the first choice against childhood bacterial meningitis in patients over 4 month old.

UR - http://www.scopus.com/inward/record.url?scp=49049121320&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=49049121320&partnerID=8YFLogxK

M3 - Article

VL - 82

SP - 187

EP - 197

JO - Nippon Densenbyo Gakkai zasshi

JF - Nippon Densenbyo Gakkai zasshi

SN - 0387-5911

IS - 3

ER -