Chiral phosphoric acid-catalyzed oxidative kinetic resolution of indolines based on transfer hydrogenation to imines

Kodai Saito, Yukihiro Shibata, Masahiro Yamanaka, Takahiko Akiyama

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73 Citations (Scopus)


The oxidative kinetic resolution of 2-substituted indoline derivatives was achieved by hydrogen transfer to imines by means of a chiral phosphoric acid catalyst. The oxidative kinetic resolution was applicable to racemic alkyl- or aryl-substituted indolines, and the remaining indolines were obtained in good yields with excellent enantioselectivities.

Original languageEnglish
Pages (from-to)11740-11743
Number of pages4
JournalJournal of the American Chemical Society
Issue number32
Publication statusPublished - 2013 Aug 14
Externally publishedYes


ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

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