Chiral synthesis of the CD ring unit of paclitaxel from D-glucal

T. Momose, M. Setoguchi, T. Fujita, H. Tamura, N. Chida

Research output: Contribution to journalArticlepeer-review

25 Citations (Scopus)

Abstract

The chiral synthesis of the fully functionalized CD ring unit of paclitaxel 3 is described; the three component coupling reaction of a cyclohexenone derived from D-glucal by way of Ferrier's carbocyclization with vinyl cuprate and formal-dehyde effectively constructed the carbon framework of 3.

Original languageEnglish
Pages (from-to)2237-2238
Number of pages2
JournalChemical Communications
Issue number22
DOIs
Publication statusPublished - 2000 Nov 21

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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