Chitosan

Mayu Hashimoto, Zhihong Yang, Yohei Koya, Toshinori Sato

Research output: Chapter in Book/Report/Conference proceedingChapter

5 Citations (Scopus)

Abstract

6 Conclusion: Chitosan possesses many favorable characteristics for use as a gene delivery system. However, further improvements in the structure and function of this system, such as optimization of chitosan (molecular weight or DDA), chemical modification using functional groups, and formation of ternary complexes, are still necessary. The results reviewed in this chapter indicate that such rational modifications to compensate for the limitations of chitosan as a gene carrier will lead to improved transfection efficiencies.

Original languageEnglish
Title of host publicationNon-viral Gene Therapy
Subtitle of host publicationGene Design and Delivery
PublisherSpringer-Verlag Tokyo
Pages63-74
Number of pages12
ISBN (Electronic)9784431278795
ISBN (Print)4431251227, 9784431251224
DOIs
Publication statusPublished - 2005 Jan 1

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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  • Cite this

    Hashimoto, M., Yang, Z., Koya, Y., & Sato, T. (2005). Chitosan. In Non-viral Gene Therapy: Gene Design and Delivery (pp. 63-74). Springer-Verlag Tokyo. https://doi.org/10.1007/4-431-27879-6_6