Chitosan

Mayu Hashimoto; Zhihong Yang; Yohei Koya; Toshinori Sato

doi:10.1007/4-431-27879-6_6

Chitosan

Mayu Hashimoto, Zhihong Yang, Yohei Koya, Toshinori Sato

Department of Biosciences and Informatics

Research output: Chapter in Book/Report/Conference proceeding › Chapter

5 Citations (Scopus)

Abstract

6 Conclusion: Chitosan possesses many favorable characteristics for use as a gene delivery system. However, further improvements in the structure and function of this system, such as optimization of chitosan (molecular weight or DDA), chemical modification using functional groups, and formation of ternary complexes, are still necessary. The results reviewed in this chapter indicate that such rational modifications to compensate for the limitations of chitosan as a gene carrier will lead to improved transfection efficiencies.

Original language	English
Title of host publication	Non-viral Gene Therapy
Subtitle of host publication	Gene Design and Delivery
Publisher	Springer-Verlag Tokyo
Pages	63-74
Number of pages	12
ISBN (Electronic)	9784431278795
ISBN (Print)	4431251227, 9784431251224
DOIs	https://doi.org/10.1007/4-431-27879-6_6
Publication status	Published - 2005

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

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10.1007/4-431-27879-6_6

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title = "Chitosan",

abstract = "6 Conclusion: Chitosan possesses many favorable characteristics for use as a gene delivery system. However, further improvements in the structure and function of this system, such as optimization of chitosan (molecular weight or DDA), chemical modification using functional groups, and formation of ternary complexes, are still necessary. The results reviewed in this chapter indicate that such rational modifications to compensate for the limitations of chitosan as a gene carrier will lead to improved transfection efficiencies.",

author = "Mayu Hashimoto and Zhihong Yang and Yohei Koya and Toshinori Sato",

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TY - CHAP

T1 - Chitosan

AU - Hashimoto, Mayu

AU - Yang, Zhihong

AU - Koya, Yohei

AU - Sato, Toshinori

PY - 2005

Y1 - 2005

N2 - 6 Conclusion: Chitosan possesses many favorable characteristics for use as a gene delivery system. However, further improvements in the structure and function of this system, such as optimization of chitosan (molecular weight or DDA), chemical modification using functional groups, and formation of ternary complexes, are still necessary. The results reviewed in this chapter indicate that such rational modifications to compensate for the limitations of chitosan as a gene carrier will lead to improved transfection efficiencies.

AB - 6 Conclusion: Chitosan possesses many favorable characteristics for use as a gene delivery system. However, further improvements in the structure and function of this system, such as optimization of chitosan (molecular weight or DDA), chemical modification using functional groups, and formation of ternary complexes, are still necessary. The results reviewed in this chapter indicate that such rational modifications to compensate for the limitations of chitosan as a gene carrier will lead to improved transfection efficiencies.

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DO - 10.1007/4-431-27879-6_6

M3 - Chapter

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SN - 9784431251224

SP - 63

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BT - Non-viral Gene Therapy

PB - Springer-Verlag Tokyo

ER -

Chitosan

Abstract

ASJC Scopus subject areas

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