Chronic Hepatitis Infected with Hepatitis GB Virus Type C/Hepatitis G Virus Presenting as Non-Alcoholic Steatohepatitis

Hidetsugu Saito; Hirotoshi Ebinuma; Shigeru Kuramochi; Hiromasa Ishii

doi:10.2169/internalmedicine.36.283

Chronic Hepatitis Infected with Hepatitis GB Virus Type C/Hepatitis G Virus Presenting as Non-Alcoholic Steatohepatitis

Hidetsugu Saito, Hirotoshi Ebinuma, Shigeru Kuramochi, Hiromasa Ishii

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

A 68-year-old man with moderate liver dysfunction diagnosed with atypical pneumonia showed serum alanine aminotransferase and γ-glutamyltranspeptidase levels which revealed a sustained abnormality over six months. Hepatitis GB virus type C/hepatitis G virus was demonstrated in his serum by reverse transcription-polymerase chain reaction. Liver histology showed steatohepatitis typically observed in alcoholic hepatitis without a remarkable drinking history. This case suggests that hepatitis GB virus type C/hepatitis G virus may induce chronic hepatitis and that there may be cases with chronic hepatitis induced by this virus in patients who have been diagnosed with alcoholic liver disease, even in cases with typical histology of alcoholic hepatitis.

Original language	English
Pages (from-to)	283-288
Number of pages	6
Journal	Internal Medicine
Volume	36
Issue number	4
DOIs	https://doi.org/10.2169/internalmedicine.36.283
Publication status	Published - 1997 Jan 1

Keywords

Alcoholic hepatitis
Atypical pneumonia
Liver biopsy
Reverse transcription-polymerase chain reaction

ASJC Scopus subject areas

Internal Medicine

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10.2169/internalmedicine.36.283

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title = "Chronic Hepatitis Infected with Hepatitis GB Virus Type C/Hepatitis G Virus Presenting as Non-Alcoholic Steatohepatitis",

abstract = "A 68-year-old man with moderate liver dysfunction diagnosed with atypical pneumonia showed serum alanine aminotransferase and γ-glutamyltranspeptidase levels which revealed a sustained abnormality over six months. Hepatitis GB virus type C/hepatitis G virus was demonstrated in his serum by reverse transcription-polymerase chain reaction. Liver histology showed steatohepatitis typically observed in alcoholic hepatitis without a remarkable drinking history. This case suggests that hepatitis GB virus type C/hepatitis G virus may induce chronic hepatitis and that there may be cases with chronic hepatitis induced by this virus in patients who have been diagnosed with alcoholic liver disease, even in cases with typical histology of alcoholic hepatitis.",

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AU - Ishii, Hiromasa

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