Chronic Immune Thrombocytopenia in Sarcoidosis

Michie Hisada; Hideaki Nakajima; Shigeru Nogawa; Yohsuke Shigeta; Ken Kawamura; Shinichiro Okamoto

doi:10.2302/kjm.39.261

Chronic Immune Thrombocytopenia in Sarcoidosis

Michie Hisada, Hideaki Nakajima, Shigeru Nogawa, Yohsuke Shigeta, Ken Kawamura, Shinichiro Okamoto

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

We report a 69 year-old female with sarcoidosis who developed chronic thrombocytopenia, a rare complication of this disorder. Histologically normal bone marrow with increased number of megakaryocytes and high level of PAIgG strongly suggest the immune destruction of platelets as the cause of thrombocytopenia. In addition to thrombocytopenia, this case is also distinctive in its clinical manifestation. The patient developed several infrequent manifestations of sarcoidosis including complete AV block, uveitis, skin eruptions and middle lobe syndrome, but, did not have an intrathoracic adenopathy, the commonest manifestation of this disease.

Original language	English
Pages (from-to)	261-264
Number of pages	4
Journal	the keio journal of medicine
Volume	39
Issue number	4
DOIs	https://doi.org/10.2302/kjm.39.261
Publication status	Published - 1990

Keywords

complete AV block
middle lobe syndrome
skin eruption
uveitis

ASJC Scopus subject areas

Medicine(all)

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10.2302/kjm.39.261

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AU - Hisada, Michie

AU - Nakajima, Hideaki

AU - Nogawa, Shigeru

AU - Shigeta, Yohsuke

AU - Kawamura, Ken

AU - Okamoto, Shinichiro

PY - 1990

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N2 - We report a 69 year-old female with sarcoidosis who developed chronic thrombocytopenia, a rare complication of this disorder. Histologically normal bone marrow with increased number of megakaryocytes and high level of PAIgG strongly suggest the immune destruction of platelets as the cause of thrombocytopenia. In addition to thrombocytopenia, this case is also distinctive in its clinical manifestation. The patient developed several infrequent manifestations of sarcoidosis including complete AV block, uveitis, skin eruptions and middle lobe syndrome, but, did not have an intrathoracic adenopathy, the commonest manifestation of this disease.

AB - We report a 69 year-old female with sarcoidosis who developed chronic thrombocytopenia, a rare complication of this disorder. Histologically normal bone marrow with increased number of megakaryocytes and high level of PAIgG strongly suggest the immune destruction of platelets as the cause of thrombocytopenia. In addition to thrombocytopenia, this case is also distinctive in its clinical manifestation. The patient developed several infrequent manifestations of sarcoidosis including complete AV block, uveitis, skin eruptions and middle lobe syndrome, but, did not have an intrathoracic adenopathy, the commonest manifestation of this disease.

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Chronic Immune Thrombocytopenia in Sarcoidosis

Abstract

Keywords

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