Chronic inflammatory demyelinating polyradiculoneuropathy in a patient with Crohn's disease

Masaki Ohyagi; Takuya Ohkubo; Yousuke Yagi; Satoru Ishibashi; Junko Akiyama; Masakazu Nagahori; Mamoru Watanabe; Takanori Yokota; Hidehiro Mizusawa

doi:10.2169/internalmedicine.52.8452

Chronic inflammatory demyelinating polyradiculoneuropathy in a patient with Crohn's disease

Masaki Ohyagi, Takuya Ohkubo, Yousuke Yagi, Satoru Ishibashi, Junko Akiyama, Masakazu Nagahori, Mamoru Watanabe, Takanori Yokota, Hidehiro Mizusawa

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

Crohn's disease (CD) is a chronic inflammatory disorder of the gastrointestinal tract that is frequently accompanied by systemic complications. Neuropathologies have not been well investigated as extraintestinal manifestations of CD. We herein report the case of a 36-year-old man with CD who presented with progressive weakness and numbness. A neurological examination and the results of a nerve conduction study and a sural nerve biopsy led to a diagnosis of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). Plasma exchanges were initially effective; however, the effects gradually declined starting 10 days after the plasma exchange (PE). These results suggest that humoral factors may play an important role in CIDP associated with CD.

Original language	English
Pages (from-to)	125-128
Number of pages	4
Journal	Internal Medicine
Volume	52
Issue number	1
DOIs	https://doi.org/10.2169/internalmedicine.52.8452
Publication status	Published - 2013
Externally published	Yes

Keywords

Chronic inflammatory demyelinating polyradiculoneuropathy
Crohn's disease
Extraintestinal manifestations
Humoral factors
Inflammatory bowel disease
Neurological complications

ASJC Scopus subject areas

Internal Medicine

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10.2169/internalmedicine.52.8452

Cite this

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abstract = "Crohn's disease (CD) is a chronic inflammatory disorder of the gastrointestinal tract that is frequently accompanied by systemic complications. Neuropathologies have not been well investigated as extraintestinal manifestations of CD. We herein report the case of a 36-year-old man with CD who presented with progressive weakness and numbness. A neurological examination and the results of a nerve conduction study and a sural nerve biopsy led to a diagnosis of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). Plasma exchanges were initially effective; however, the effects gradually declined starting 10 days after the plasma exchange (PE). These results suggest that humoral factors may play an important role in CIDP associated with CD.",

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AU - Ohyagi, Masaki

AU - Ohkubo, Takuya

AU - Yagi, Yousuke

AU - Ishibashi, Satoru

AU - Akiyama, Junko

AU - Nagahori, Masakazu

AU - Watanabe, Mamoru

AU - Yokota, Takanori

AU - Mizusawa, Hidehiro

PY - 2013

Y1 - 2013

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AB - Crohn's disease (CD) is a chronic inflammatory disorder of the gastrointestinal tract that is frequently accompanied by systemic complications. Neuropathologies have not been well investigated as extraintestinal manifestations of CD. We herein report the case of a 36-year-old man with CD who presented with progressive weakness and numbness. A neurological examination and the results of a nerve conduction study and a sural nerve biopsy led to a diagnosis of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). Plasma exchanges were initially effective; however, the effects gradually declined starting 10 days after the plasma exchange (PE). These results suggest that humoral factors may play an important role in CIDP associated with CD.

KW - Chronic inflammatory demyelinating polyradiculoneuropathy

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KW - Extraintestinal manifestations

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KW - Inflammatory bowel disease

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Chronic inflammatory demyelinating polyradiculoneuropathy in a patient with Crohn's disease

Abstract

Keywords

ASJC Scopus subject areas

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