Chronic inflammatory demyelinating polyradiculoneuropathy in a patient with Crohn's disease

Masaki Ohyagi, Takuya Ohkubo, Yousuke Yagi, Satoru Ishibashi, Junko Akiyama, Masakazu Nagahori, Mamoru Watanabe, Takanori Yokota, Hidehiro Mizusawa

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)


Crohn's disease (CD) is a chronic inflammatory disorder of the gastrointestinal tract that is frequently accompanied by systemic complications. Neuropathologies have not been well investigated as extraintestinal manifestations of CD. We herein report the case of a 36-year-old man with CD who presented with progressive weakness and numbness. A neurological examination and the results of a nerve conduction study and a sural nerve biopsy led to a diagnosis of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). Plasma exchanges were initially effective; however, the effects gradually declined starting 10 days after the plasma exchange (PE). These results suggest that humoral factors may play an important role in CIDP associated with CD.

Original languageEnglish
Pages (from-to)125-128
Number of pages4
JournalInternal Medicine
Issue number1
Publication statusPublished - 2013
Externally publishedYes


  • Chronic inflammatory demyelinating polyradiculoneuropathy
  • Crohn's disease
  • Extraintestinal manifestations
  • Humoral factors
  • Inflammatory bowel disease
  • Neurological complications

ASJC Scopus subject areas

  • Internal Medicine


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