Circadian pattern of fibrillatory events in non-Brugada-type idiopathic ventricular fibrillation with a focus on J waves

Yoshiyasu Aizawa, Masahito Sato, Seiko Ohno, Minoru Horie, Seiji Takatsuki, Keiichi Fukuda, Masaomi Chinushi, Tatsuya Usui, Kazutaka Aonuma, Yukio Hosaka, Michel Haissaguerre, Yoshifusa Aizawa

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Background The circadian pattern of ventricular fibrillation (VF) episodes in patients with idiopathic ventricular fibrillation (IVF) is poorly understood.

Methods Excluding Brugada syndrome and other primary electrical diseases, the circadian pattern of VF occurrence was determined in 64 patients with IVF. The clinical and electrocardiographic characteristics were compared among patients with nocturnal (midnight to 6:00 AM) VF and nonnocturnal VF in relation to J waves. A J wave was defined as either notching or a slur at the QRS terminal >0.1 mV above the isoelectric line in contiguous leads.

Results The overall distribution pattern of VF occurrence showed 2 peaks at approximately 6:00 AM and around 8:00 PM. Nocturnal VF was observed in 20 patients (31.3%), and J waves were present in 14 of these 20 individuals (70.0%), whereas J waves were less frequent in the 44 nonnocturnal patients with VF: 16 (36.4%) (P =.0117). Among patients with J waves, nocturnal VF was observed in 46.7% with a peak at approximately 4:00 AM. Nocturnal VF was less common in patients without J waves, occurring in only 17.6% (P =.0124). Both the type and location of J waves and the pattern of the ST segment were similar between the nocturnal and nonnocturnal VF groups. J waves were associated with a VF storm and long-term arrhythmia recurrence.

Conclusion In IVF, the presence of J waves may characterize a higher nocturnal incidence of VF and a higher acute and chronic risk of recurrence.

Original languageEnglish
Pages (from-to)2261-2266
Number of pages6
JournalHeart Rhythm
Volume11
Issue number12
DOIs
Publication statusPublished - 2014 Dec 1

Fingerprint

Ventricular Fibrillation
Paroxysmal ventricular fibrillation
Brugada Syndrome
Recurrence
Cardiac Arrhythmias

Keywords

  • Circadian rhythm
  • Idiopathic ventricular fibrillation
  • J waves
  • Sudden cardiac death
  • Ventricular fibrillation

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)

Cite this

Circadian pattern of fibrillatory events in non-Brugada-type idiopathic ventricular fibrillation with a focus on J waves. / Aizawa, Yoshiyasu; Sato, Masahito; Ohno, Seiko; Horie, Minoru; Takatsuki, Seiji; Fukuda, Keiichi; Chinushi, Masaomi; Usui, Tatsuya; Aonuma, Kazutaka; Hosaka, Yukio; Haissaguerre, Michel; Aizawa, Yoshifusa.

In: Heart Rhythm, Vol. 11, No. 12, 01.12.2014, p. 2261-2266.

Research output: Contribution to journalArticle

Aizawa, Y, Sato, M, Ohno, S, Horie, M, Takatsuki, S, Fukuda, K, Chinushi, M, Usui, T, Aonuma, K, Hosaka, Y, Haissaguerre, M & Aizawa, Y 2014, 'Circadian pattern of fibrillatory events in non-Brugada-type idiopathic ventricular fibrillation with a focus on J waves', Heart Rhythm, vol. 11, no. 12, pp. 2261-2266. https://doi.org/10.1016/j.hrthm.2014.08.022
Aizawa, Yoshiyasu ; Sato, Masahito ; Ohno, Seiko ; Horie, Minoru ; Takatsuki, Seiji ; Fukuda, Keiichi ; Chinushi, Masaomi ; Usui, Tatsuya ; Aonuma, Kazutaka ; Hosaka, Yukio ; Haissaguerre, Michel ; Aizawa, Yoshifusa. / Circadian pattern of fibrillatory events in non-Brugada-type idiopathic ventricular fibrillation with a focus on J waves. In: Heart Rhythm. 2014 ; Vol. 11, No. 12. pp. 2261-2266.
@article{613239dadeef4a5b83ffe2c5f038f742,
title = "Circadian pattern of fibrillatory events in non-Brugada-type idiopathic ventricular fibrillation with a focus on J waves",
abstract = "Background The circadian pattern of ventricular fibrillation (VF) episodes in patients with idiopathic ventricular fibrillation (IVF) is poorly understood.Methods Excluding Brugada syndrome and other primary electrical diseases, the circadian pattern of VF occurrence was determined in 64 patients with IVF. The clinical and electrocardiographic characteristics were compared among patients with nocturnal (midnight to 6:00 AM) VF and nonnocturnal VF in relation to J waves. A J wave was defined as either notching or a slur at the QRS terminal >0.1 mV above the isoelectric line in contiguous leads.Results The overall distribution pattern of VF occurrence showed 2 peaks at approximately 6:00 AM and around 8:00 PM. Nocturnal VF was observed in 20 patients (31.3{\%}), and J waves were present in 14 of these 20 individuals (70.0{\%}), whereas J waves were less frequent in the 44 nonnocturnal patients with VF: 16 (36.4{\%}) (P =.0117). Among patients with J waves, nocturnal VF was observed in 46.7{\%} with a peak at approximately 4:00 AM. Nocturnal VF was less common in patients without J waves, occurring in only 17.6{\%} (P =.0124). Both the type and location of J waves and the pattern of the ST segment were similar between the nocturnal and nonnocturnal VF groups. J waves were associated with a VF storm and long-term arrhythmia recurrence.Conclusion In IVF, the presence of J waves may characterize a higher nocturnal incidence of VF and a higher acute and chronic risk of recurrence.",
keywords = "Circadian rhythm, Idiopathic ventricular fibrillation, J waves, Sudden cardiac death, Ventricular fibrillation",
author = "Yoshiyasu Aizawa and Masahito Sato and Seiko Ohno and Minoru Horie and Seiji Takatsuki and Keiichi Fukuda and Masaomi Chinushi and Tatsuya Usui and Kazutaka Aonuma and Yukio Hosaka and Michel Haissaguerre and Yoshifusa Aizawa",
year = "2014",
month = "12",
day = "1",
doi = "10.1016/j.hrthm.2014.08.022",
language = "English",
volume = "11",
pages = "2261--2266",
journal = "Heart Rhythm",
issn = "1547-5271",
publisher = "Elsevier",
number = "12",

}

TY - JOUR

T1 - Circadian pattern of fibrillatory events in non-Brugada-type idiopathic ventricular fibrillation with a focus on J waves

AU - Aizawa, Yoshiyasu

AU - Sato, Masahito

AU - Ohno, Seiko

AU - Horie, Minoru

AU - Takatsuki, Seiji

AU - Fukuda, Keiichi

AU - Chinushi, Masaomi

AU - Usui, Tatsuya

AU - Aonuma, Kazutaka

AU - Hosaka, Yukio

AU - Haissaguerre, Michel

AU - Aizawa, Yoshifusa

PY - 2014/12/1

Y1 - 2014/12/1

N2 - Background The circadian pattern of ventricular fibrillation (VF) episodes in patients with idiopathic ventricular fibrillation (IVF) is poorly understood.Methods Excluding Brugada syndrome and other primary electrical diseases, the circadian pattern of VF occurrence was determined in 64 patients with IVF. The clinical and electrocardiographic characteristics were compared among patients with nocturnal (midnight to 6:00 AM) VF and nonnocturnal VF in relation to J waves. A J wave was defined as either notching or a slur at the QRS terminal >0.1 mV above the isoelectric line in contiguous leads.Results The overall distribution pattern of VF occurrence showed 2 peaks at approximately 6:00 AM and around 8:00 PM. Nocturnal VF was observed in 20 patients (31.3%), and J waves were present in 14 of these 20 individuals (70.0%), whereas J waves were less frequent in the 44 nonnocturnal patients with VF: 16 (36.4%) (P =.0117). Among patients with J waves, nocturnal VF was observed in 46.7% with a peak at approximately 4:00 AM. Nocturnal VF was less common in patients without J waves, occurring in only 17.6% (P =.0124). Both the type and location of J waves and the pattern of the ST segment were similar between the nocturnal and nonnocturnal VF groups. J waves were associated with a VF storm and long-term arrhythmia recurrence.Conclusion In IVF, the presence of J waves may characterize a higher nocturnal incidence of VF and a higher acute and chronic risk of recurrence.

AB - Background The circadian pattern of ventricular fibrillation (VF) episodes in patients with idiopathic ventricular fibrillation (IVF) is poorly understood.Methods Excluding Brugada syndrome and other primary electrical diseases, the circadian pattern of VF occurrence was determined in 64 patients with IVF. The clinical and electrocardiographic characteristics were compared among patients with nocturnal (midnight to 6:00 AM) VF and nonnocturnal VF in relation to J waves. A J wave was defined as either notching or a slur at the QRS terminal >0.1 mV above the isoelectric line in contiguous leads.Results The overall distribution pattern of VF occurrence showed 2 peaks at approximately 6:00 AM and around 8:00 PM. Nocturnal VF was observed in 20 patients (31.3%), and J waves were present in 14 of these 20 individuals (70.0%), whereas J waves were less frequent in the 44 nonnocturnal patients with VF: 16 (36.4%) (P =.0117). Among patients with J waves, nocturnal VF was observed in 46.7% with a peak at approximately 4:00 AM. Nocturnal VF was less common in patients without J waves, occurring in only 17.6% (P =.0124). Both the type and location of J waves and the pattern of the ST segment were similar between the nocturnal and nonnocturnal VF groups. J waves were associated with a VF storm and long-term arrhythmia recurrence.Conclusion In IVF, the presence of J waves may characterize a higher nocturnal incidence of VF and a higher acute and chronic risk of recurrence.

KW - Circadian rhythm

KW - Idiopathic ventricular fibrillation

KW - J waves

KW - Sudden cardiac death

KW - Ventricular fibrillation

UR - http://www.scopus.com/inward/record.url?scp=84919346917&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84919346917&partnerID=8YFLogxK

U2 - 10.1016/j.hrthm.2014.08.022

DO - 10.1016/j.hrthm.2014.08.022

M3 - Article

C2 - 25131664

AN - SCOPUS:84919346917

VL - 11

SP - 2261

EP - 2266

JO - Heart Rhythm

JF - Heart Rhythm

SN - 1547-5271

IS - 12

ER -