Cis-acting elements involved in the G2/M-phase-specific transcription of the cyclin B gene in the unicellular alga Cyanidioschyzon merolae

Nobuko Sumiya

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

M-specific activator (MSA) cis-acting elements have been determined to be involved in the regulation of G2/M-phase-specific transcription in spermatophytes. In this study, the involvement of MSA-core elements in G2/M-phase-specific transcription was examined in the unicellular red alga Cyanidioschyzon merolae. In the C. merolae genome, MSA-core elements do not accumulate specifically in the upstream of mitosis-specific transcriptional genes. Mutations of the four MSA-core elements of the cyclin B gene, which encodes a central factor of the G2-to-M-phase transition, have resulted in the abolishment of transcription or permission of transcription even in the G1 phase. These results suggest that all four MSA-core elements located in the upstream region of cyclin B are involved in G2/M-phase-specific transcription in C. merolae; however, the nature of the involvement of MSA-core elements in G2/M-phase-specific transcription differed among the four elements. Thus, MSA-core-element-mediated G2/M-phase-specific transcription in C. merolae seems to be regulated by a complex mechanism.

Original languageEnglish
Pages (from-to)1301-1310
Number of pages10
JournalJournal of Plant Research
Volume134
Issue number6
DOIs
Publication statusPublished - 2021 Nov

Keywords

  • Cell cycle
  • Cyanidioschyzon merolae
  • Cyclin B
  • G2/M-phase

ASJC Scopus subject areas

  • Plant Science

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