Clinical application of living-related conjunctival-limbal allograft

Kazuo Tsubota, Shigeto Shimmura, Naoshi Shinozaki, Edward J. Holland, Jun Shimazaki

Research output: Contribution to journalArticlepeer-review

22 Citations (Scopus)


PURPOSE: To report one successful case of conjunctival-limbal allograft for the treatment of a severe ocular surface disorder. METHODS: Interventional case report. A 9-year-old patient suffering from Stevens-Johnson syndrome with total keratinization of the ocular surface of both eyes was treated in the left eye by corneal and conjunctival stem cell transplantation. Oral cyclosporin A and topical autologous serum and corticosteroids were administered. RESULTS: Mucosal epithelial phenotype was maintained in the left eye at most recent examination for more than 3 years after ocular surface reconstruction. CONCLUSION: A total keratinized ocular surface may be treated with the combination of conjunctival and corneal stem cell transplantation.

Original languageEnglish
Pages (from-to)134-135
Number of pages2
JournalAmerican Journal of Ophthalmology
Issue number1
Publication statusPublished - 2002
Externally publishedYes

ASJC Scopus subject areas

  • Ophthalmology


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