Clinical features of mycoplasma pneumoniae infections in the 2010 epidemic season

Report of two cases with unusual presentations

Tomoaki Takei, Miyuki Morozumi, Hirohiko Ozaki, Hisayo Fujita, Kimiko Ubukata, Isshi Kobayashi, Keisuke Kadota, Takako Miyamae, Shumpei Yokota, Satoshi Iwata, Takashi Takahashi

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Mycoplasma pneumoniae (Mp) is one of the main pathogens causing community-acquired pneumonia, particularly in young individuals. Host immune response appears to play an important role in prolonged symptoms, as well as in the recent increasing prevalence of drug-resistant Mp isolated from patients. Case 1 had a prolonged clinical course caused by drug-resistant Mp and received steroid therapy despite Mp susceptibility to some antimicrobial agents. Serum cytokine profiles revealed elevation of interleukin-6/-10 and interferon-γ in acute phase. Case 2 had mycoplasmal myocarditis without any respiratory symptoms, which resolved spontaneously without the administration of any antimicrobial agent. These observations suggest that host immune response probably contributes to the etiology of Mp-associated complications.

Original languageEnglish
Pages (from-to)402-405
Number of pages4
JournalPediatrics and Neonatology
Volume54
Issue number6
DOIs
Publication statusPublished - 2013 Dec
Externally publishedYes

Fingerprint

Mycoplasma pneumoniae
Infection
Anti-Infective Agents
Myocarditis
Pharmaceutical Preparations
Interleukin-10
Interferons
Interleukin-6
Pneumonia
Steroids
Cytokines
Serum

Keywords

  • cytokine
  • drug resistance
  • Mycoplasma pneumoniae
  • myocarditis
  • steroid

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Clinical features of mycoplasma pneumoniae infections in the 2010 epidemic season : Report of two cases with unusual presentations. / Takei, Tomoaki; Morozumi, Miyuki; Ozaki, Hirohiko; Fujita, Hisayo; Ubukata, Kimiko; Kobayashi, Isshi; Kadota, Keisuke; Miyamae, Takako; Yokota, Shumpei; Iwata, Satoshi; Takahashi, Takashi.

In: Pediatrics and Neonatology, Vol. 54, No. 6, 12.2013, p. 402-405.

Research output: Contribution to journalArticle

Takei, T, Morozumi, M, Ozaki, H, Fujita, H, Ubukata, K, Kobayashi, I, Kadota, K, Miyamae, T, Yokota, S, Iwata, S & Takahashi, T 2013, 'Clinical features of mycoplasma pneumoniae infections in the 2010 epidemic season: Report of two cases with unusual presentations', Pediatrics and Neonatology, vol. 54, no. 6, pp. 402-405. https://doi.org/10.1016/j.pedneo.2012.11.016
Takei, Tomoaki ; Morozumi, Miyuki ; Ozaki, Hirohiko ; Fujita, Hisayo ; Ubukata, Kimiko ; Kobayashi, Isshi ; Kadota, Keisuke ; Miyamae, Takako ; Yokota, Shumpei ; Iwata, Satoshi ; Takahashi, Takashi. / Clinical features of mycoplasma pneumoniae infections in the 2010 epidemic season : Report of two cases with unusual presentations. In: Pediatrics and Neonatology. 2013 ; Vol. 54, No. 6. pp. 402-405.
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