Clinical features of mycoplasma pneumoniae infections in the 2010 epidemic season: Report of two cases with unusual presentations

Tomoaki Takei, Miyuki Morozumi, Hirohiko Ozaki, Hisayo Fujita, Kimiko Ubukata, Isshi Kobayashi, Keisuke Kadota, Takako Miyamae, Shumpei Yokota, Satoshi Iwata, Takashi Takahashi

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Mycoplasma pneumoniae (Mp) is one of the main pathogens causing community-acquired pneumonia, particularly in young individuals. Host immune response appears to play an important role in prolonged symptoms, as well as in the recent increasing prevalence of drug-resistant Mp isolated from patients. Case 1 had a prolonged clinical course caused by drug-resistant Mp and received steroid therapy despite Mp susceptibility to some antimicrobial agents. Serum cytokine profiles revealed elevation of interleukin-6/-10 and interferon-γ in acute phase. Case 2 had mycoplasmal myocarditis without any respiratory symptoms, which resolved spontaneously without the administration of any antimicrobial agent. These observations suggest that host immune response probably contributes to the etiology of Mp-associated complications.

Original languageEnglish
Pages (from-to)402-405
Number of pages4
JournalPediatrics and Neonatology
Volume54
Issue number6
DOIs
Publication statusPublished - 2013 Dec 1

Keywords

  • Mycoplasma pneumoniae
  • cytokine
  • drug resistance
  • myocarditis
  • steroid

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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    Takei, T., Morozumi, M., Ozaki, H., Fujita, H., Ubukata, K., Kobayashi, I., Kadota, K., Miyamae, T., Yokota, S., Iwata, S., & Takahashi, T. (2013). Clinical features of mycoplasma pneumoniae infections in the 2010 epidemic season: Report of two cases with unusual presentations. Pediatrics and Neonatology, 54(6), 402-405. https://doi.org/10.1016/j.pedneo.2012.11.016