Clinical information on serum IGFBP-3 levels and IGFBP-3 proteolytic activity in childhood

Yukihiro Hasegawa, Tomonobu Hasegawa, Katsura Fujii, Hideko Konii, Makoto Anzo, Taiji Aso, Shinobu Kotoh, Yutaka Tsuchiya

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

In this review paper, three pieces of clinical information in childhood are presented: (1) IGFBP-3 may replace GH provocation tests in the diagnosis of GH deficiency (GHD); (2) IGFBP-3 levels are regulated by IGF-I levels in a short period, and (3) ratio of free IGF-I to total IGF-I is high in serum of early infancy, similarly to serum of pregnancy, only partially owing to the presence of IGFBP-3 proteolytic activity. Each paper will be published soon.

Original languageEnglish
Pages (from-to)457-463
Number of pages7
JournalProgress in Growth Factor Research
Volume6
Issue number2-4
DOIs
Publication statusPublished - 1995

Fingerprint

Insulin-Like Growth Factor Binding Protein 3
Insulin-Like Growth Factor I
Serum
Pregnancy

Keywords

  • IGFBP-3
  • IGFBP-3 proteolytic activity

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology
  • Endocrinology, Diabetes and Metabolism
  • Immunology and Allergy

Cite this

Clinical information on serum IGFBP-3 levels and IGFBP-3 proteolytic activity in childhood. / Hasegawa, Yukihiro; Hasegawa, Tomonobu; Fujii, Katsura; Konii, Hideko; Anzo, Makoto; Aso, Taiji; Kotoh, Shinobu; Tsuchiya, Yutaka.

In: Progress in Growth Factor Research, Vol. 6, No. 2-4, 1995, p. 457-463.

Research output: Contribution to journalArticle

Hasegawa, Yukihiro ; Hasegawa, Tomonobu ; Fujii, Katsura ; Konii, Hideko ; Anzo, Makoto ; Aso, Taiji ; Kotoh, Shinobu ; Tsuchiya, Yutaka. / Clinical information on serum IGFBP-3 levels and IGFBP-3 proteolytic activity in childhood. In: Progress in Growth Factor Research. 1995 ; Vol. 6, No. 2-4. pp. 457-463.
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