Clinical manifestations of Bacillus cereus meningitis in newborn infants

K. Tokieda, Y. Morikawa, K. Maeyama, K. Mori, K. Ikeda

Research output: Contribution to journalArticlepeer-review

30 Citations (Scopus)


Bacillus cereus (B. cereus) meningitis sometimes occurs in patients with risk factors, which are associated with central nervous system (CNS) anomalies, surgical or anaesthetic access to CNS. We observed two cases of B. cereus meningitis in neonates without such risk factors. The clinical courses of both neonates were fulminant, and routine antibiotic therapy failed. Intracranial haemorrhage was evident at autopsy. According to the previous neonatal case reports and our experience, we found that six of seven neonates were premature babies admitted to the neonatal intensive care unit, five died within a week of onset of the disease, and six had intracranial haemorrhage. We speculate that B. cereus meningitis may occur in neonates, even without any of the risk factors previously described in adult case reports, and that the clinical manifestations of the meningitis might be characterized by the high incidence of intracranial haemorrhage and poor mortality.

Original languageEnglish
Pages (from-to)582-584
Number of pages3
JournalJournal of Paediatrics and Child Health
Issue number6
Publication statusPublished - 1999


  • Bacillus cereus
  • Intracranial haemorrhage
  • Meningitis
  • Neonate

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


Dive into the research topics of 'Clinical manifestations of Bacillus cereus meningitis in newborn infants'. Together they form a unique fingerprint.

Cite this