Clinical Practice Guidelines for the Management of Atopic Dermatitis 2016

Hidehisa Saeki, Takeshi Nakahara, Akio Tanaka, Kenji Kabashima, Makoto Sugaya, Hiroyuki Murota, Tamotsu Ebihara, Yoko Kataoka, Michiko Aihara, Takafumi Etoh, Norito Katoh

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Atopic dermatitis (AD) is a disease characterized by relapsing eczema with pruritus as a primary lesion. Most patients have an atopic predisposition. The definitive diagnosis of AD requires the presence of all three features: (i) pruritus; (ii) typical morphology and distribution of the eczema; and (iii) chronic and chronically relapsing course. The current strategies to treat AD in Japan from the perspective of evidence-based medicine consist of three primary measures: (i) the use of topical corticosteroids and tacrolimus ointment as the main treatment for the inflammation; (ii) topical application of emollients to treat the cutaneous barrier dysfunction; and (iii) avoidance of apparent exacerbating factors, psychological counseling and advice about daily life. The guidelines present recommendations to review clinical research articles, evaluate the balance between the advantages and disadvantages of medical activities, and optimize medical activity-related patient outcomes with respect to several important points requiring decision-making in clinical practice.

Original languageEnglish
JournalJournal of Dermatology
Publication statusAccepted/In press - 2016



  • Atopic dermatitis
  • Clinical practice guideline
  • Diagnosis
  • Evidence-based medicine
  • Treatment

ASJC Scopus subject areas

  • Dermatology

Cite this

Saeki, H., Nakahara, T., Tanaka, A., Kabashima, K., Sugaya, M., Murota, H., Ebihara, T., Kataoka, Y., Aihara, M., Etoh, T., & Katoh, N. (Accepted/In press). Clinical Practice Guidelines for the Management of Atopic Dermatitis 2016. Journal of Dermatology.