Abstract
We studied biapenem (BIPM), a new carbapenem antibiotic, in terms of postoperative penetration into peritoneal exudate. We measured daily concentration of BIPM in peritoneal exudate after radical gastrectomy for gastric cancer or gastric leiomyosarcoma for 3 days. BIPM was administered by intravenous drip infusion at a dose of 0.3 g twice a day. The average concentrations in peritoneal exudate in 3 patients were 0.68, 0.33 and 0.11 μg/ml on days 1, 2 and 3, respectively. No side effects and no abnormal laboratory findings were observed.
| Original language | English |
|---|---|
| Pages (from-to) | 683-685 |
| Number of pages | 3 |
| Journal | Chemotherapy |
| Volume | 42 |
| Issue number | SUPPL. 4 |
| Publication status | Published - 1994 |
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ASJC Scopus subject areas
- Pharmacology
Cite this
Clinical studies on penetration of biapenem to postoperative peritoneal exudate. / Ishibiki, K.; Saikawa, Y.; Shibata, S.
In: Chemotherapy, Vol. 42, No. SUPPL. 4, 1994, p. 683-685.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Clinical studies on penetration of biapenem to postoperative peritoneal exudate
AU - Ishibiki, K.
AU - Saikawa, Y.
AU - Shibata, S.
PY - 1994
Y1 - 1994
N2 - We studied biapenem (BIPM), a new carbapenem antibiotic, in terms of postoperative penetration into peritoneal exudate. We measured daily concentration of BIPM in peritoneal exudate after radical gastrectomy for gastric cancer or gastric leiomyosarcoma for 3 days. BIPM was administered by intravenous drip infusion at a dose of 0.3 g twice a day. The average concentrations in peritoneal exudate in 3 patients were 0.68, 0.33 and 0.11 μg/ml on days 1, 2 and 3, respectively. No side effects and no abnormal laboratory findings were observed.
AB - We studied biapenem (BIPM), a new carbapenem antibiotic, in terms of postoperative penetration into peritoneal exudate. We measured daily concentration of BIPM in peritoneal exudate after radical gastrectomy for gastric cancer or gastric leiomyosarcoma for 3 days. BIPM was administered by intravenous drip infusion at a dose of 0.3 g twice a day. The average concentrations in peritoneal exudate in 3 patients were 0.68, 0.33 and 0.11 μg/ml on days 1, 2 and 3, respectively. No side effects and no abnormal laboratory findings were observed.
UR - http://www.scopus.com/inward/record.url?scp=0028576810&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0028576810&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:0028576810
VL - 42
SP - 683
EP - 685
JO - Chemotherapy
JF - Chemotherapy
SN - 0009-3165
IS - SUPPL. 4
ER -