Co-existence of acute myeloid leukemia with multilineage dysplasia and Epstein-Barr virus-associated T-cell lymphoproliferative disorder in a patient with rheumatoid arthritis

a case report.

Michihide Tokuhira, Kyoko Hanzawa, Reiko Watanabe, Yasunobu Sekiguchi, Tomoe Nemoto, Yasuo Toyozumi, Jun ichi Tamaru, Shinji Itoyama, Katsuya Suzuki, Hideto Kameda, Shigehisa Mori, Masahiro Kizaki

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Rheumatoid arthritis (RA) is an autoimmune disease mediated by inflammatory processes mainly at the joints. Recently, awareness of Epstein-Barr virus (EBV)-associated T-cell lymphoproliferative disorder (T-LPD) has been heightened for its association with methotraxate usage in RA patients. In the contrary, acute myeloid leukemia with multilineage dysplasia (AML-MLD) has never been documented to be present concomitantly with the above two conditions. In this report we present a case of an autopsy-proven co-existence of AML-MLD and EBV-associated T-LPD in a patient with RA.

Original languageEnglish
Pages (from-to)27
Number of pages1
JournalJournal of hematology & oncology
Volume2
Publication statusPublished - 2009
Externally publishedYes

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Lymphoproliferative Disorders
Human Herpesvirus 4
Acute Myeloid Leukemia
Rheumatoid Arthritis
T-Lymphocytes
Autoimmune Diseases
Autopsy
Joints

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Co-existence of acute myeloid leukemia with multilineage dysplasia and Epstein-Barr virus-associated T-cell lymphoproliferative disorder in a patient with rheumatoid arthritis : a case report. / Tokuhira, Michihide; Hanzawa, Kyoko; Watanabe, Reiko; Sekiguchi, Yasunobu; Nemoto, Tomoe; Toyozumi, Yasuo; Tamaru, Jun ichi; Itoyama, Shinji; Suzuki, Katsuya; Kameda, Hideto; Mori, Shigehisa; Kizaki, Masahiro.

In: Journal of hematology & oncology, Vol. 2, 2009, p. 27.

Research output: Contribution to journalArticle

Tokuhira, M, Hanzawa, K, Watanabe, R, Sekiguchi, Y, Nemoto, T, Toyozumi, Y, Tamaru, JI, Itoyama, S, Suzuki, K, Kameda, H, Mori, S & Kizaki, M 2009, 'Co-existence of acute myeloid leukemia with multilineage dysplasia and Epstein-Barr virus-associated T-cell lymphoproliferative disorder in a patient with rheumatoid arthritis: a case report.', Journal of hematology & oncology, vol. 2, pp. 27.
Tokuhira, Michihide ; Hanzawa, Kyoko ; Watanabe, Reiko ; Sekiguchi, Yasunobu ; Nemoto, Tomoe ; Toyozumi, Yasuo ; Tamaru, Jun ichi ; Itoyama, Shinji ; Suzuki, Katsuya ; Kameda, Hideto ; Mori, Shigehisa ; Kizaki, Masahiro. / Co-existence of acute myeloid leukemia with multilineage dysplasia and Epstein-Barr virus-associated T-cell lymphoproliferative disorder in a patient with rheumatoid arthritis : a case report. In: Journal of hematology & oncology. 2009 ; Vol. 2. pp. 27.
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abstract = "Rheumatoid arthritis (RA) is an autoimmune disease mediated by inflammatory processes mainly at the joints. Recently, awareness of Epstein-Barr virus (EBV)-associated T-cell lymphoproliferative disorder (T-LPD) has been heightened for its association with methotraxate usage in RA patients. In the contrary, acute myeloid leukemia with multilineage dysplasia (AML-MLD) has never been documented to be present concomitantly with the above two conditions. In this report we present a case of an autopsy-proven co-existence of AML-MLD and EBV-associated T-LPD in a patient with RA.",
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AU - Nemoto, Tomoe

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AU - Tamaru, Jun ichi

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AU - Suzuki, Katsuya

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AU - Mori, Shigehisa

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