CO laser angioplasty system: efficacy of manipulatable laser angioscope catheter

Tsunenori Arai, Makoto Kikuchi, Kyoichi M.D. Mizuno, Masami Sakurada, Akira M.D. Miyamoto, Koh Arakawa, Akira Kurita, Haruo M.D. Nakamura, Kiyoshi Takeuchi, Atsushi Utsumi, Yoshiro Akai

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)


A percutaneous transluminal coronary angioplasty system using a unique combination of CO laser (5 μm) and As-S infrared glass fiber under the guidance of a manipulatable laser angioscope catheter is described. The ablation and guidance functions of this system are evaluated. The angioplasty treatment procedure under angioscope guidance was studied by in vitro model experiment and in vivo animal experiment. The whole angioplasty system is newly developed. That is, a transportable compact medical CO laser device which can emit up to 10 W, a 5 F manipulatable laser angioscope catheter, a thin CO laser cable of which the diameter is 0.6 mm, an angioscope imaging system for laser ablation guidance, and a system controller were developed. Anesthetized adult mongrel dogs (n = 5) with an artificial complete occlusion in the femoral artery and an artificial human vessel model including occluded or stenotic coronary artery were used. The manipulatability of the catheter was drastically improved (both rotation and bending), therefore, precise control of ablation to expand stenosis was obtained. A 90% artificial stenosis made of human yellow plaque in 4.0 mm diameter in the vessel was expanded to 70% stenosis by repetitive CO laser ablations of which total energy was 220 J. All procedures were performed and controlled under angioscope visualization.

Original languageEnglish
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
PublisherPubl by Int Soc for Optical Engineering
Number of pages6
ISBN (Print)081940795X
Publication statusPublished - 1992
Externally publishedYes
EventOptical Fibers in Medicine VII - Los Angeles, CA, USA
Duration: 1992 Jan 211992 Jan 22

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
ISSN (Print)0277-786X


OtherOptical Fibers in Medicine VII
CityLos Angeles, CA, USA

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering


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