Abstract
The oxidative kinetic resolution of secondary alcohols using molecular oxygen and olefins was catalyzed by the optically active ketoiminatocobalt(II) complexes. The various secondary benzylic alcohols were subjected to the aerobic oxidative reaction to afford optically active alcohols of high ee along with the corresponding ketones in high yield. The oxidation of the deuterated alcohols revealed that the accompanying olefin mediated the oxidation for conversion to the corresponding α-deuterated ketones.
| Original language | English |
|---|---|
| Pages (from-to) | 40-41 |
| Number of pages | 2 |
| Journal | Chemistry Letters |
| Volume | 38 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 2009 |
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ASJC Scopus subject areas
- Chemistry(all)
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Cobalt-catalyzed oxidative kinetic resolution of secondary benzylic alcohols with molecular oxygen. / Yamada, Tohru; Higano, Sho; Yano, Takanori; Yamashita, Yoshihiro.
In: Chemistry Letters, Vol. 38, No. 1, 2009, p. 40-41.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Cobalt-catalyzed oxidative kinetic resolution of secondary benzylic alcohols with molecular oxygen
AU - Yamada, Tohru
AU - Higano, Sho
AU - Yano, Takanori
AU - Yamashita, Yoshihiro
PY - 2009
Y1 - 2009
N2 - The oxidative kinetic resolution of secondary alcohols using molecular oxygen and olefins was catalyzed by the optically active ketoiminatocobalt(II) complexes. The various secondary benzylic alcohols were subjected to the aerobic oxidative reaction to afford optically active alcohols of high ee along with the corresponding ketones in high yield. The oxidation of the deuterated alcohols revealed that the accompanying olefin mediated the oxidation for conversion to the corresponding α-deuterated ketones.
AB - The oxidative kinetic resolution of secondary alcohols using molecular oxygen and olefins was catalyzed by the optically active ketoiminatocobalt(II) complexes. The various secondary benzylic alcohols were subjected to the aerobic oxidative reaction to afford optically active alcohols of high ee along with the corresponding ketones in high yield. The oxidation of the deuterated alcohols revealed that the accompanying olefin mediated the oxidation for conversion to the corresponding α-deuterated ketones.
UR - http://www.scopus.com/inward/record.url?scp=67650503792&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=67650503792&partnerID=8YFLogxK
U2 - 10.1246/cl.2009.40
DO - 10.1246/cl.2009.40
M3 - Article
AN - SCOPUS:67650503792
VL - 38
SP - 40
EP - 41
JO - Chemistry Letters
JF - Chemistry Letters
SN - 0366-7022
IS - 1
ER -