Coexpression of a Multidrug-resistance Gene(MDR1) and Herpes Simplex Virus Thymidine Kinase Gene as Part of a Bicistronic Messenger RNA in a Retrovirus Vector Allows Selective Killing of MDR1-transduced Cells

Yoshikazu Sugimoto, Ivan Aksentijevich, Michael M. Gottesman

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Medicine & Life Sciences