Combination of familial Barlow's disease with bilateral axillary artery aneurysms in two brothers

Hirofumi Kasahara, Mikihiko Kudo, Ryohei Yozu, Susumu Hosoda, Akira Shiikawa

Research output: Contribution to journalArticle

1 Citation (Scopus)


We encountered two brothers with a combination of Barlow's disease and bilateral axillary artery aneurysms who were operated on during their third decade of life. A symmetrical form of true bilateral axillary artery aneurysms is uncommon. Recurrent mitral regurgitation was presented in the older brother with an endocardial defect in the left atrium, suggesting connective tissue fragility. A hereditary connective tissue disorder was strongly suspected because of the similar presentation and an unusual cluster of pathologies in siblings. Careful follow-up is required to detect recurrence of mitral regurgitation or aneurysm formation in other vessels.

Original languageEnglish
Pages (from-to)115-117
Number of pages3
JournalGeneral thoracic and cardiovascular surgery
Issue number2
Publication statusPublished - 2012 Feb 1



  • Barlow's disease
  • Bilateral axillary artery aneurysms
  • Connective tissue disorder
  • Recurrent mitral regurgitation

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine

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