Compact acoustic-resolution photoacoustic imaging system with fiber-based illumination

Yasuyuki Tsunoi, Shunichi Sato, Ryota Watanabe, Satoko Kawauchi, Hiroshi Ashida, Mitsuhiro Terakawa

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Acoustic-resolution photoacoustic imaging enables unique high-resolution visualization of chromophores in deep tissue. However, most current systems are bulky and use complex optical components for illumination. In this study, we developed a compact acoustic-resolution photoacoustic imaging system with simple fiber-based illumination. Around the ultrasound sensor attached to an acoustic lens, four optical fibers were placed in four directions 90° apart, and the sensor plane was covered with an optically and acoustically transparent plastic spacer. The imaging head is compact (diameter, 32 mm; height, 27mm) and lightweight (32 g) and is alignment-free, thus being suitable for in vivo applications. We assessed the uniformity and symmetry of photoacoustic excitation both by Monte Carlo simulation and experiments. A phantom study showed lateral and axial resolutions of the system to be 148 and 66 innodatamum, respectively. With the system, high-contrast visualization of blood vessels in rat skin was demonstrated in vivo.

Original languageEnglish
Article number126701
JournalJapanese Journal of Applied Physics
Volume53
Issue number12
DOIs
Publication statusPublished - 2014 Dec 1

Fingerprint

Photoacoustic effect
Imaging systems
Lighting
Acoustics
illumination
fibers
acoustics
Fibers
Visualization
Acoustic imaging
Imaging techniques
blood vessels
sensors
Sensors
Blood vessels
Chromophores
spacers
chromophores
rats
Rats

ASJC Scopus subject areas

  • Engineering(all)
  • Physics and Astronomy(all)

Cite this

Compact acoustic-resolution photoacoustic imaging system with fiber-based illumination. / Tsunoi, Yasuyuki; Sato, Shunichi; Watanabe, Ryota; Kawauchi, Satoko; Ashida, Hiroshi; Terakawa, Mitsuhiro.

In: Japanese Journal of Applied Physics, Vol. 53, No. 12, 126701, 01.12.2014.

Research output: Contribution to journalArticle

Tsunoi, Yasuyuki ; Sato, Shunichi ; Watanabe, Ryota ; Kawauchi, Satoko ; Ashida, Hiroshi ; Terakawa, Mitsuhiro. / Compact acoustic-resolution photoacoustic imaging system with fiber-based illumination. In: Japanese Journal of Applied Physics. 2014 ; Vol. 53, No. 12.
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