Comparison of atheromatous tissue ablation between CO laser and excimer laser irradiations

Tsunenori Arai, M. Nakagawa, M. Kikuchi, K. Mizuno, A. Miyamoto, Y. Okamoto, K. Satomura, T. Shibuya, K. Arakawa, K. Isojima, A. Kurita, H. Nakamura, A. Utsumi, Y. Akai, M. Katoh, K. Takeuchi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

UV (XeCl, XeF excimer) and IR (CO, Er:YAG) lasers are of interest for laser angioplasty owing to their restricted light penetration in living tissue, which prevents vascular perforation. The authors investigated the quantitative ablation rate of vascular tissue, both normal and diseased, by IR (CO) and UV (XeCl, XeF) lasers to determine the optimum laser wavelength for which selective ablation is achieved. All experiments were done in vitro. The results show that CO laser radiation preferentially ablates the yellow atheroma with an affinity factor of 1.8. This affinity factor can be attributed to the low melting (and/or vaporizing) point of fatty materials following thermal ablation by the CO laser. However, XeF laser radiation exhibits an inverse affinity (affinity factor of 0.6). A normal layer of the vascular wall contains more proteins than yellow plaque, so that the absorption of UV lasers in the normal vascular wall may be greater than in the plaque.

Original languageEnglish
Title of host publicationCONFERENCE ON LASERS AND ELECTRO-0PTICS
Editors Anon
PublisherPubl by IEEE
Pages48-49
Number of pages2
ISBN (Print)1557520860
Publication statusPublished - 1989
Externally publishedYes
EventSummaries of Papers Presented at the Conference on Lasers and Electro-Optics - Baltimore, MD, USA
Duration: 1989 Apr 241989 Apr 28

Other

OtherSummaries of Papers Presented at the Conference on Lasers and Electro-Optics
CityBaltimore, MD, USA
Period89/4/2489/4/28

Fingerprint

Excimer lasers
Laser beam effects
Ablation
Tissue
Lasers
Laser radiation
Vaporization
Melting
Proteins
Wavelength
Experiments

ASJC Scopus subject areas

  • Engineering(all)

Cite this

Arai, T., Nakagawa, M., Kikuchi, M., Mizuno, K., Miyamoto, A., Okamoto, Y., ... Takeuchi, K. (1989). Comparison of atheromatous tissue ablation between CO laser and excimer laser irradiations. In Anon (Ed.), CONFERENCE ON LASERS AND ELECTRO-0PTICS (pp. 48-49). Publ by IEEE.

Comparison of atheromatous tissue ablation between CO laser and excimer laser irradiations. / Arai, Tsunenori; Nakagawa, M.; Kikuchi, M.; Mizuno, K.; Miyamoto, A.; Okamoto, Y.; Satomura, K.; Shibuya, T.; Arakawa, K.; Isojima, K.; Kurita, A.; Nakamura, H.; Utsumi, A.; Akai, Y.; Katoh, M.; Takeuchi, K.

CONFERENCE ON LASERS AND ELECTRO-0PTICS. ed. / Anon. Publ by IEEE, 1989. p. 48-49.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Arai, T, Nakagawa, M, Kikuchi, M, Mizuno, K, Miyamoto, A, Okamoto, Y, Satomura, K, Shibuya, T, Arakawa, K, Isojima, K, Kurita, A, Nakamura, H, Utsumi, A, Akai, Y, Katoh, M & Takeuchi, K 1989, Comparison of atheromatous tissue ablation between CO laser and excimer laser irradiations. in Anon (ed.), CONFERENCE ON LASERS AND ELECTRO-0PTICS. Publ by IEEE, pp. 48-49, Summaries of Papers Presented at the Conference on Lasers and Electro-Optics, Baltimore, MD, USA, 89/4/24.
Arai T, Nakagawa M, Kikuchi M, Mizuno K, Miyamoto A, Okamoto Y et al. Comparison of atheromatous tissue ablation between CO laser and excimer laser irradiations. In Anon, editor, CONFERENCE ON LASERS AND ELECTRO-0PTICS. Publ by IEEE. 1989. p. 48-49
Arai, Tsunenori ; Nakagawa, M. ; Kikuchi, M. ; Mizuno, K. ; Miyamoto, A. ; Okamoto, Y. ; Satomura, K. ; Shibuya, T. ; Arakawa, K. ; Isojima, K. ; Kurita, A. ; Nakamura, H. ; Utsumi, A. ; Akai, Y. ; Katoh, M. ; Takeuchi, K. / Comparison of atheromatous tissue ablation between CO laser and excimer laser irradiations. CONFERENCE ON LASERS AND ELECTRO-0PTICS. editor / Anon. Publ by IEEE, 1989. pp. 48-49
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abstract = "UV (XeCl, XeF excimer) and IR (CO, Er:YAG) lasers are of interest for laser angioplasty owing to their restricted light penetration in living tissue, which prevents vascular perforation. The authors investigated the quantitative ablation rate of vascular tissue, both normal and diseased, by IR (CO) and UV (XeCl, XeF) lasers to determine the optimum laser wavelength for which selective ablation is achieved. All experiments were done in vitro. The results show that CO laser radiation preferentially ablates the yellow atheroma with an affinity factor of 1.8. This affinity factor can be attributed to the low melting (and/or vaporizing) point of fatty materials following thermal ablation by the CO laser. However, XeF laser radiation exhibits an inverse affinity (affinity factor of 0.6). A normal layer of the vascular wall contains more proteins than yellow plaque, so that the absorption of UV lasers in the normal vascular wall may be greater than in the plaque.",
author = "Tsunenori Arai and M. Nakagawa and M. Kikuchi and K. Mizuno and A. Miyamoto and Y. Okamoto and K. Satomura and T. Shibuya and K. Arakawa and K. Isojima and A. Kurita and H. Nakamura and A. Utsumi and Y. Akai and M. Katoh and K. Takeuchi",
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AU - Kikuchi, M.

AU - Mizuno, K.

AU - Miyamoto, A.

AU - Okamoto, Y.

AU - Satomura, K.

AU - Shibuya, T.

AU - Arakawa, K.

AU - Isojima, K.

AU - Kurita, A.

AU - Nakamura, H.

AU - Utsumi, A.

AU - Akai, Y.

AU - Katoh, M.

AU - Takeuchi, K.

PY - 1989

Y1 - 1989

N2 - UV (XeCl, XeF excimer) and IR (CO, Er:YAG) lasers are of interest for laser angioplasty owing to their restricted light penetration in living tissue, which prevents vascular perforation. The authors investigated the quantitative ablation rate of vascular tissue, both normal and diseased, by IR (CO) and UV (XeCl, XeF) lasers to determine the optimum laser wavelength for which selective ablation is achieved. All experiments were done in vitro. The results show that CO laser radiation preferentially ablates the yellow atheroma with an affinity factor of 1.8. This affinity factor can be attributed to the low melting (and/or vaporizing) point of fatty materials following thermal ablation by the CO laser. However, XeF laser radiation exhibits an inverse affinity (affinity factor of 0.6). A normal layer of the vascular wall contains more proteins than yellow plaque, so that the absorption of UV lasers in the normal vascular wall may be greater than in the plaque.

AB - UV (XeCl, XeF excimer) and IR (CO, Er:YAG) lasers are of interest for laser angioplasty owing to their restricted light penetration in living tissue, which prevents vascular perforation. The authors investigated the quantitative ablation rate of vascular tissue, both normal and diseased, by IR (CO) and UV (XeCl, XeF) lasers to determine the optimum laser wavelength for which selective ablation is achieved. All experiments were done in vitro. The results show that CO laser radiation preferentially ablates the yellow atheroma with an affinity factor of 1.8. This affinity factor can be attributed to the low melting (and/or vaporizing) point of fatty materials following thermal ablation by the CO laser. However, XeF laser radiation exhibits an inverse affinity (affinity factor of 0.6). A normal layer of the vascular wall contains more proteins than yellow plaque, so that the absorption of UV lasers in the normal vascular wall may be greater than in the plaque.

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