Comparison of image reconstruction algorithms in myocardial perfusion scintigraphy

J. Bai, J. Hashimoto, T. Suzuki, Tadaki Nakahara, A. Kubo, S. Iwanaga, H. Mitamura, S. Ogawa

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

The purpose of this study was to compare the clinical utility of two image reconstruction algorithms in myocardial perfusion SPECT (single-photon emission computed tomography): filtered back-projection (FBP) and ordered subset expectation maximization (OSEM). A rest/stress one-day protocol with 99mTc-MIBI or tetrofosmin was performed on 102 consecutive patients who underwent coronary angiography. After SPECT data acquisition, images were reconstructed with FBP and OSEM algorithms. We assessed diagnostic performance (sensitivity, specificity and accuracy) in detecting coronary artery stenosis and evaluated regional tracer uptake with a 4-point scoring system. Although there were no significant differences in diagnostic performance between FBP and OSEM reconstruction, the OSEM method yielded higher uptake in the RCA area than the FBP method by reducing the count-loss artifact due to hepatic uptake of the tracers. In addition, regional uptake in the LCX area was significantly lower in the OSEM image than in the FBP image; this phenomenon was observed mainly in patients with coronary stenosis and/or infarction in the LCX territory. In conclusion, OSEM and FBP offered comparable diagnostic performance in stress myocardial perfusion SPECT. The OSEM method contributed to reduction of the count-loss artifact in inferior and posterior walls and to easy recognition of hypoperfusion in the LCX area.

Original languageEnglish
Pages (from-to)79-83
Number of pages5
JournalAnnals of Nuclear Medicine
Volume15
Issue number1
Publication statusPublished - 2001

Fingerprint

Myocardial Perfusion Imaging
Perfusion Imaging
Computer-Assisted Image Processing
Single-Photon Emission-Computed Tomography
Coronary Stenosis
Artifacts
Perfusion
Coronary Angiography
Infarction
Sensitivity and Specificity
Liver

Keywords

  • Image reconstruction
  • Myocardial perfusion scintigraphy
  • OSEM algorithm
  • Tc-99m-MIBI
  • Tc-99m-tetrofosmin

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Bai, J., Hashimoto, J., Suzuki, T., Nakahara, T., Kubo, A., Iwanaga, S., ... Ogawa, S. (2001). Comparison of image reconstruction algorithms in myocardial perfusion scintigraphy. Annals of Nuclear Medicine, 15(1), 79-83.

Comparison of image reconstruction algorithms in myocardial perfusion scintigraphy. / Bai, J.; Hashimoto, J.; Suzuki, T.; Nakahara, Tadaki; Kubo, A.; Iwanaga, S.; Mitamura, H.; Ogawa, S.

In: Annals of Nuclear Medicine, Vol. 15, No. 1, 2001, p. 79-83.

Research output: Contribution to journalArticle

Bai, J, Hashimoto, J, Suzuki, T, Nakahara, T, Kubo, A, Iwanaga, S, Mitamura, H & Ogawa, S 2001, 'Comparison of image reconstruction algorithms in myocardial perfusion scintigraphy', Annals of Nuclear Medicine, vol. 15, no. 1, pp. 79-83.
Bai, J. ; Hashimoto, J. ; Suzuki, T. ; Nakahara, Tadaki ; Kubo, A. ; Iwanaga, S. ; Mitamura, H. ; Ogawa, S. / Comparison of image reconstruction algorithms in myocardial perfusion scintigraphy. In: Annals of Nuclear Medicine. 2001 ; Vol. 15, No. 1. pp. 79-83.
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