Comparison of mortality between Japanese peritoneal dialysis and hemodialysis patients: A 5-year multicenter follow-up study

Kazuko Suzuki, Tsuneo Konta, Kazunobu Ichikawa, Ami Ikeda, Hiroki Niino, Masato Hoshikawa, Toshiyuki Takahashi, Hiroshi Abiko, Minoru Ito, Ikuto Masakane, Tomohito Matsunaga, Kosuke Kudo, Hiroko Sato, Noriyuki Degawa, Isao Kubota

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Abstract

To examine the relationship between dialysis modality and prognosis in Japanese patients, we conducted a prospective multicenter observational study. We recruited 83 background-matched peritoneal dialysis (PD) and 83 hemodialysis (HD) patients (average age, 64.9 years; men, 53.6%; diabetic patients, 22.9%; median duration of dialysis, 48 months in all patients) and followed them for 5 years. During the follow-up period, 27 PD patients (16 cardiovascular and 11 non-cardiovascular deaths) and 27 HD patients died (14 cardiovascular and 13 non-cardiovascular deaths). There were 8 PD patients switched to HD, and 6 PD patients received renal transplantation. Kaplan-Meier analysis revealed that the crude survival rate was not significantly different at the end of 5 years (PD 67.5% versus 67.5%, log-rank P=0.719). The difference in cardiovascular and non-cardiovascular mortalities between PD and HD was not statistically significant. Multivariate Cox analysis showed that the independent predictors for death were age and serum albumin levels, but not the dialysis modality. This study showed that the overall mortality was not significantly different between PD and HD patients, which suggests that dialysis modality might not be an independent factor for survival in Japanese patients.

Original languageEnglish
Article number231018
JournalInternational Journal of Nephrology
Volume2012
DOIs
Publication statusPublished - 2012
Externally publishedYes

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ASJC Scopus subject areas

  • Nephrology

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Suzuki, K., Konta, T., Ichikawa, K., Ikeda, A., Niino, H., Hoshikawa, M., Takahashi, T., Abiko, H., Ito, M., Masakane, I., Matsunaga, T., Kudo, K., Sato, H., Degawa, N., & Kubota, I. (2012). Comparison of mortality between Japanese peritoneal dialysis and hemodialysis patients: A 5-year multicenter follow-up study. International Journal of Nephrology, 2012, [231018]. https://doi.org/10.1155/2012/231018