Comparison of patient acceptance of sodium phosphate versus polyethylene glycol plus sodium picosulfate for colon cleansing in Japanese

Naoki Hosoe, Manabu Nakashita, Hiroyuki Imaeda, Tomohisa Sujino, Rieko Bessho, Riko Ichikawa, Nagamu Inoue, Takanori Kanai, Toshifumi Hibi, Haruhiko Ogata

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Background and Aim: In Japan, patient acceptance of bowel preparation methods before colonoscopy remains unknown. This study was conducted to evaluate the patient acceptance of sodium phosphate (NaP) tablets and polyethylene glycol solution (PEG) with sodium picosulfate. Methods: One hundred patients were randomized into one of the following two groups: the NaP tablet first-use group or the PEG with sodium picosulfate first-use group in a crossover design trial. Patient acceptance and incidence of adverse events were evaluated using a questionnaire. Colon-cleansing effectiveness was also evaluated. Results: Patients' overall impressions of the preparations were significantly different between the NaP tablet (77.9%, 67/86) and PEG with sodium picosulfate (60.5%, 52/86; P=0.001). Nausea incidence as an adverse event was significantly different between the two regimens (P=0.03). Colon-cleansing effectiveness was not significantly different between the two regimens. Conclusions: The results of this crossover study showed that patient acceptance was similar to those previously reported in a parallel-group comparison. In Japanese patients, preference for and acceptance of NaP tablets was significantly higher than that for PEG with sodium picosulfate solution.

Original languageEnglish
Pages (from-to)1617-1622
Number of pages6
JournalJournal of Gastroenterology and Hepatology (Australia)
Volume27
Issue number10
DOIs
Publication statusPublished - 2012 Oct

Keywords

  • Colonoscopy
  • Laxatives
  • Polyethylene glycols
  • Sodium phosphate

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

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