TY - JOUR
T1 - Comparison of radiological characteristics between diffuse idiopathic skeletal hyperostosis and ankylosing spondylitis
T2 - a multicenter study
AU - Takahashi, Takuya
AU - Yoshii, Toshitaka
AU - Mori, Kanji
AU - Kobayashi, Shigeto
AU - Inoue, Hisashi
AU - Tada, Kurisu
AU - Tamura, Naoto
AU - Hirai, Takashi
AU - Sugimura, Nobuhiro
AU - Nagoshi, Narihito
AU - Maki, Satoshi
AU - Katsumi, Keiichi
AU - Koda, Masao
AU - Murata, Kazuma
AU - Takeuchi, Kazuhiro
AU - Nakashima, Hiroaki
AU - Imagama, Shiro
AU - Kawaguchi, Yoshiharu
AU - Yamazaki, Masashi
AU - Okawa, Atsushi
N1 - Funding Information:
This work was supported by a Health and Labour Science Research grant (number 201610008B) and a grant from the Japan Agency for Medical Research and Development (number 16ek0109136h0002).
Publisher Copyright:
© 2023, The Author(s).
PY - 2023/12
Y1 - 2023/12
N2 - To evaluate the radiological differences between diffuse idiopathic skeletal hyperostosis (DISH) and ankylosing spondylitis (AS) using whole spine computed tomography (CT), including the spine and sacroiliac joint (SIJ). The ossification and bridging of spinal ligament and fusion of the facet joint and SIJ were evaluated in 111 patients who were diagnosed with DISH and 27 patients with AS on the whole spine CT. The number of anterior bridging and shape of bridging (candle-wax-type/ smooth-type) were also evaluated. We further evaluated patients with DISH and AS by matching their age and sex. Complete SIJ fusion was more common in AS, whereas anterior and posterior bony bridging around SIJ was more common in DISH. However, 63% of patients with DISH had a partial or complete fusion. In spinal anterior bony bridging, the majority of patients with AS had the smooth-type, whereas those with DISH had the candle-wax-type. However, some of the patients with DISH (11%) had smooth-type. Intervertebral facet joint fusion is more common in AS. The number of anterior spinal bony bridging was greater in AS than in DISH, especially in the lumbar spine. These results are useful in differentiating DISH from AS and should therefore be considered when making a diagnosis.
AB - To evaluate the radiological differences between diffuse idiopathic skeletal hyperostosis (DISH) and ankylosing spondylitis (AS) using whole spine computed tomography (CT), including the spine and sacroiliac joint (SIJ). The ossification and bridging of spinal ligament and fusion of the facet joint and SIJ were evaluated in 111 patients who were diagnosed with DISH and 27 patients with AS on the whole spine CT. The number of anterior bridging and shape of bridging (candle-wax-type/ smooth-type) were also evaluated. We further evaluated patients with DISH and AS by matching their age and sex. Complete SIJ fusion was more common in AS, whereas anterior and posterior bony bridging around SIJ was more common in DISH. However, 63% of patients with DISH had a partial or complete fusion. In spinal anterior bony bridging, the majority of patients with AS had the smooth-type, whereas those with DISH had the candle-wax-type. However, some of the patients with DISH (11%) had smooth-type. Intervertebral facet joint fusion is more common in AS. The number of anterior spinal bony bridging was greater in AS than in DISH, especially in the lumbar spine. These results are useful in differentiating DISH from AS and should therefore be considered when making a diagnosis.
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U2 - 10.1038/s41598-023-28946-w
DO - 10.1038/s41598-023-28946-w
M3 - Article
C2 - 36725891
AN - SCOPUS:85147218468
SN - 2045-2322
VL - 13
JO - Scientific Reports
JF - Scientific Reports
IS - 1
M1 - 1849
ER -