Complement component 9 deficiency is not a susceptibility factor for SLE

S. Kanemitsu, K. Ihara, R. Kira, Y. Kaku, K. Sakai, K. Tsuzaka, T. Takeuchi, T. Hara

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Almost all complement component 9 (C9) deficiency in Japan shows Arg95Stop mutation of C9 gene. Therefore, we studied the prevalence of Arg95Stop mutation of C9 gene among 78 patients with SLE to elucidate the assocation of SLE and C9 deficiency. The Arg95Stop carrier frequency showed no significant difference between SLE patients and controls. Thus, C9 deficiency is not implicated in SLE susceptibility.

Original languageEnglish
Pages (from-to)456-457
Number of pages2
JournalLupus
Volume9
Issue number6
DOIs
Publication statusPublished - 2000

Keywords

  • Collagen disease
  • Complement deficiency
  • Meningococcal meningitis
  • Nonsense mutation

ASJC Scopus subject areas

  • Rheumatology

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  • Cite this

    Kanemitsu, S., Ihara, K., Kira, R., Kaku, Y., Sakai, K., Tsuzaka, K., Takeuchi, T., & Hara, T. (2000). Complement component 9 deficiency is not a susceptibility factor for SLE. Lupus, 9(6), 456-457. https://doi.org/10.1191/096120300678828523